Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repairNucleases in homologous recombination as targets for cancer therapyYeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast.Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA.Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombinationMEK and TGF-beta Inhibition Promotes Reprogramming without the Use of Transcription FactorRole of PCNA and TLS polymerases in D-loop extension during homologous recombination in humansRad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination.Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52.Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity.Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA associationSrs2: the "Odd-Job Man" in DNA repair.Rad52 SUMOylation affects the efficiency of the DNA repair.A versatile scaffold contributes to damage survival via sumoylation and nuclease interactionsReconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activitiesRad51 recombinase and recombination mediators.Sumoylation influences DNA break repair partly by increasing the solubility of a conserved end resection protein.Homologous recombination and its regulationRecombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.Sumoylation regulates EXO1 stability and processing of DNA damage.Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylationLif1 SUMOylation and its role in non-homologous end-joining.Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption.Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediator and the Srs2 anti-recombinase.Strand invasion by HLTF as a mechanism for template switch in fork rescue.Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome.Role of PCNA and RFC in promoting Mus81-complex activity.Phosphorylation of Elg1 regulates its activity.Interaction with Rad51 is indispensable for recombination mediator function of Rad52.Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein.ATPase and DNA helicase activities of the Saccharomyces cerevisiae anti-recombinase Srs2.Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p.RECQ4 selectively recognizes Holliday junctions.
P50
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P50
description
hulumtues
@sq
researcher
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ricercatore
@it
wetenschapper
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հետազոտող
@hy
name
Lumir Krejci
@ast
Lumir Krejci
@es
Lumir Krejci
@nl
Lumir Krejci
@sl
Lumír Krejčí
@cs
Lumír Krejčí
@en
type
label
Lumir Krejci
@ast
Lumir Krejci
@es
Lumir Krejci
@nl
Lumir Krejci
@sl
Lumír Krejčí
@cs
Lumír Krejčí
@en
prefLabel
Lumir Krejci
@ast
Lumir Krejci
@es
Lumir Krejci
@nl
Lumir Krejci
@sl
Lumír Krejčí
@cs
Lumír Krejčí
@en
P214
P106
P19
P21
P214
P31
P496
0000-0002-4732-1405
P569
1972-03-30T00:00:00Z