Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. - Wikidata - awgldk - TriplyDB

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.

http://www.wikidata.org/entity/Q33755338

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A comprehensive glossary of autophagy-related molecules and processes (2nd edition)Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy The autophagy-lysosomal system in subarachnoid haemorrhage Inhibition of regulated cell death by cell-penetrating peptides Cancer therapy in the necroptosis era Cutting through the complexities of mTOR for the treatment of stroke Photoreceptor cell death and rescue in retinal detachment and degenerations Autophagy in the physiology and pathology of the central nervous system The mechanism of necroptosis in normal and cancer cells Targeting the apoptosis pathway in hematologic malignancies The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization Placental autophagy regulation by the BOK-MCL1 rheostat Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies.Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia 5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Inhibits RIPK1/RIPK3-Dependent Necroptosis in THP-1-Derived Foam Cells.Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells Mcl-1 ubiquitination: unique regulation of an essential survival protein.Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik.RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells.Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics.WISP1: Clinical insights for a proliferative and restorative member of the CCN family A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation.Taking aim at Alzheimer's disease through the mammalian target of rapamycin Optimization of circulating biomarkers of obatoclax-induced cell death in patients with small cell lung cancer.Shikonin kills glioma cells through necroptosis mediated by RIP-1 Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling.Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia.Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate Glucocorticoid dose determines osteocyte cell fate.CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism.Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling.

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P2860

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.

http://www.wikidata.org/entity/Q33755338

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Induction of autophagy-depende ...... ome glucocorticoid resistance.

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Induction of autophagy-depende ...... ome glucocorticoid resistance.

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type

label

Induction of autophagy-depende ...... ome glucocorticoid resistance.

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Induction of autophagy-depende ...... ome glucocorticoid resistance.

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prefLabel

Induction of autophagy-depende ...... ome glucocorticoid resistance.

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Induction of autophagy-depende ...... ome glucocorticoid resistance.

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Journal of Clinical Investigation

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Induction of autophagy-depende ...... come glucocorticoid resistance

@en

P2093

Gunnar Cario

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Laura Bonapace

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Maike Schmitz

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Martin Schrappe

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Martin Stanulla

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Urs Ziegler

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P2860

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

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1310-1323

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10.1172/JCI39987

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4

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120

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Beat C Bornhauser

Jean-Pierre Bourquin

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2010-04-01T00:00:00Z

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20200450

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2846044

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