about
Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 familyCa2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heartHuman alpha and beta parvalbumins. Structure and tissue-specific expressionS100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cellsThe LIM-only protein FHL2 is a negative regulator of E4F1Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytesThe second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex diseaseUnpeaceful roles of mutant PAX proteins in cancerPurification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACYThe human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2The S100 family of EF-hand calcium-binding proteins: functions and pathologyCharacterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein familyCharacterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21Cell-based small-molecule compound screen identifies fenretinide as potential therapeutic for translocation-positive rhabdomyosarcomaA novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300Prediction of chromosomal aneuploidy from gene expression data.Identification of novel DNA binding sites recognized by the transcription factor mPOU (POU6F1).Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic-homing peptide LyP-1.Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcomaInduction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.S100 proteins in Corpora amylacea from normal human brain.CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheresThe transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin).Rhabdomyosarcoma: current challenges and their implications for developing therapies.The MLL recombinome of acute leukemias in 2013.PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.The primary structure of chicken B-creatine kinase and evidence for heterogeneity of its mRNA.The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma.The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells.Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1.Prenatal origin of separate evolution of leukemia in identical twins.Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma.The MLL recombinome of acute leukemias in 2017.FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.
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Beat Schafer
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Beat Schafer
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Beat Schafer
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