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Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancerMelanoma genome sequencing reveals frequent PREX2 mutationsPathways and therapeutic targets in melanomaMelanoma: from mutations to medicineEGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated GenesMolecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: DETERMINANTS OF DNA BINDING AND REDOX REGULATION BY DISULFIDE BOND FORMATION.A small molecule that binds and inhibits the ETV1 transcription factor oncoproteinMolecular pathways: targeting ETS gene fusions in cancer.Personalized oncology through integrative high-throughput sequencing: a pilot study.The ETS family of oncogenic transcription factors in solid tumours.Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)MITF in melanoma: mechanisms behind its expression and activity.COP1, the negative regulator of ETV1, influences prognosis in triple-negative breast cancer.Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells.Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis.Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contextsMetastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanomaETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.Delving into somatic variation in sporadic melanoma.Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation.Comprehensive Analysis of ETS Family Members in Melanoma by Fluorescence In Situ Hybridization Reveals Recurrent ETV1 Amplification.14-3-3 proteins modulate the ETS transcription factor ETV1 in prostate cancer.Advances in melanoma senescence and potential clinical application.Genomic and biochemical insights into the specificity of ETS transcription factors.Spotlight on the role of COP1 in tumorigenesis.Targeting MAPK pathway in melanoma therapy.Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition.Copy number variation in archival melanoma biopsies versus benign melanocytic lesions.Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1.MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases.A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.ETV1 positively regulates transcription of tumor suppressor ARF.ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.Molecular Mechanism of β-Catenin Signaling Pathway Inactivation in ETV1-Positive Prostate Cancers.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An oncogenic role for ETV1 in melanoma.
@ast
An oncogenic role for ETV1 in melanoma.
@en
type
label
An oncogenic role for ETV1 in melanoma.
@ast
An oncogenic role for ETV1 in melanoma.
@en
prefLabel
An oncogenic role for ETV1 in melanoma.
@ast
An oncogenic role for ETV1 in melanoma.
@en
P2093
P2860
P50
P1433
P1476
An oncogenic role for ETV1 in melanoma.
@en
P2093
Alissa C Baker
Aurora C Dibner
David E Fisher
Judit Jané-Valbuena
Krishna G Vijayendran
Laura A Johnson
Lyn M Duncan
Sven Perner
William C Hahn
William M Lin
P2860
P304
P356
10.1158/0008-5472.CAN-09-3092
P407
P577
2010-02-16T00:00:00Z