Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformers - Wikidata - awgldk - TriplyDB

Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformers

Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformers

http://www.wikidata.org/entity/Q33762496

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Early Bunyavirus-Host Cell Interactions Human Parechovirus 1 Infection Occurs via αVβ1 Integrin Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor Multivalent presentation of antihantavirus peptides on nanoparticles enhances infection blockade Pathogenic hantaviruses direct the adherence of quiescent platelets to infected endothelial cells.Hantavirus infections for the clinician: from case presentation to diagnosis and treatment.Hypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway.Endothelial cell dysfunction in viral hemorrhage and edema.Phage display selection of cyclic peptides that inhibit Andes virus infection.Andes virus recognition of human and Syrian hamster beta3 integrins is determined by an L33P substitution in the PSI domain.Immunogenetic factors affecting susceptibility of humans and rodents to hantaviruses and the clinical course of hantaviral disease in humans.Hantavirus interferon regulation and virulence determinants Pathogenic hantaviruses Andes virus and Hantaan virus induce adherens junction disassembly by directing vascular endothelial cadherin internalization in human endothelial cells Sangassou virus, the first hantavirus isolate from Africa, displays genetic and functional properties distinct from those of other murinae-associated hantaviruses.Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans.Andes virus regulation of cellular microRNAs contributes to hantavirus-induced endothelial cell permeability.Virus interactions with endothelial cell receptors: implications for viral pathogenesis.VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability The C-terminal 42 residues of the Tula virus Gn protein regulate interferon induction.The major cellular sterol regulatory pathway is required for Andes virus infection The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responses.Productive dengue virus infection of human endothelial cells is directed by heparan sulfate-containing proteoglycan receptors.T cells are not required for pathogenesis in the Syrian hamster model of hantavirus pulmonary syndrome.Andes virus infection of lymphatic endothelial cells causes giant cell and enhanced permeability responses that are rapamycin and vascular endothelial growth factor C sensitive.Elevated VEGF Levels in Pulmonary Edema Fluid and PBMCs from Patients with Acute Hantavirus Pulmonary Syndrome.Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability.Small molecule inhibitors of hantavirus infection The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation.Amino Acid Sequences Mediating Vascular Cell Adhesion Molecule 1 Binding to Integrin Alpha 4: Homologous DSP Sequence Found for JC Polyoma VP1 Coat Protein The Andes Virus Nucleocapsid Protein Directs Basal Endothelial Cell Permeability by Activating RhoA.An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein.Vascular endothelial growth factor levels in dobrava/belgrade virus infections.Host cell factors in filovirus entry: novel players, new insights Hantavirus Gn and Gc envelope glycoproteins: key structural units for virus cell entry and virus assembly Beyond RGD: virus interactions with integrins.Low affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection.Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts.Recognition of decay accelerating factor and alpha(v)beta(3) by inactivated hantaviruses: Toward the development of high-throughput screening flow cytometry assays.A Molecular-Level Account of the Antigenic Hantaviral Surface.

P2860

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P2860

Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformers

http://www.wikidata.org/entity/Q33762496

description

2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005 թվականի հունվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Pathogenic hantaviruses bind p ...... lphavbeta3 integrin conformers

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Pathogenic hantaviruses bind p ...... lphavbeta3 integrin conformers

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Pathogenic hantaviruses bind p ...... lphavbeta3 integrin conformers

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Proceedings of the National Academy of Sciences of the United States of America

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Pathogenic hantaviruses bind p ...... lphavbeta3 integrin conformers

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P2093

Elena Gorbunova

http://www.w3.org/2001/XMLSchema#string

Erich R Mackow

http://www.w3.org/2001/XMLSchema#string

Irina N Gavrilovskaya

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Tracy Raymond

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P2860

Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties

Crystal structure of the extracellular segment of integrin alpha Vbeta3

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin

Hantaviruses: A Global Disease Problem

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

Cell migration: integrating signals from front to back

Platelet alphaIIbbeta3 recombinant autoantibodies from the B-cell repertoire of a post-transfusion purpura patient.

Cellular receptors and hantavirus pathogenesis.

The VP8 fragment of VP4 is the rhesus rotavirus hemagglutinin.

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102

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