Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: role of phosphorylation, protein trafficking, and regulatory factors.
about
Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3.Proximal nephronGastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human.NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cellsCharacterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin.Na+/H+ exchangers: physiology and link to hypertension and organ ischemia.Effect of renal lipid accumulation on proximal tubule Na+/H+ exchange and ammonium secretion.Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis.Luminal Na(+)/H (+) exchange in the proximal tubuleDopamine acutely decreases apical membrane Na/H exchanger NHE3 protein in mouse renal proximal tubule.PDZ-domain interactions and apical expression of type IIa Na/P(i) cotransporters.NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.Reduction of renal triglyceride accumulation: effects on proximal tubule Na+/H+ exchange and urinary acidification.Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation siteConcerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3.A dibasic motif involved in parathyroid hormone-induced down-regulation of the type IIa NaPi cotransporterAcid sensing in renal epithelial cells.Na-H Exchanger Isoform-2 (NHE2) Mediates Butyrate-dependent Na+ Absorption in Dextran Sulfate Sodium (DSS)-induced ColitisRegulation of transport in the connecting tubule and cortical collecting ductNovel roles of intracrine angiotensin II and signalling mechanisms in kidney cells.Selective knockdown of AT1 receptors by RNA interference inhibits Val5-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells.Intracellular ANG II directly induces in vitro transcription of TGF-beta1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors.Dose-dependent effects of angiotensin-(1-7) on the NHE3 exchanger and [Ca(2+)](i) in in vivo proximal tubules.Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3Trafficking of Na-K-ATPase and dopamine receptor molecules induced by changes in intracellular sodium concentration of renal epithelial cells.Activation of the mineralocorticoid receptor increases striatin levelsAcute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor.The biophysical and molecular basis of intracellular pH sensing by Na+/H+ exchanger-3The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking.Recent Updates on the Proximal Tubule Renin-Angiotensin System in Angiotensin II-Dependent Hypertension.G-protein-coupled receptor-mediated traffic of Na,K-ATPase to the plasma membrane requires the binding of adaptor protein 1 to a Tyr-255-based sequence in the alpha-subunit.Carbachol-mediated endocytosis of NHE3 involves a clathrin-independent mechanism requiring lipid rafts and Cdc42.Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860
Q24323099-9438C9F8-2390-407E-B4DF-983D07DE97ADQ28388052-6203C9D5-7559-4A99-A3D7-9259726054C3Q30414992-93342066-311F-443B-A693-679AC682CE3FQ33727744-2B35FF2E-1BD3-4E74-A6D5-F85560DF7BA0Q33816681-55FDD814-8784-41A4-9438-B2F1907547EFQ33818214-2B5BE676-3BE8-4647-AA53-497695F1A0B9Q33818226-68D26DB6-5765-4BD0-96F7-68A35E85FF3AQ33818281-47D1FC9E-E18D-48DA-A2A9-453D0F85FD2CQ33818285-559578F2-B23E-47C1-A3F0-F574CEEDBB4BQ33884278-31DE5F8F-217C-4C38-AF19-E4E07C9483F5Q33966441-581D1472-EC0B-477D-8CAB-53403179851EQ34154837-F97FE22A-F686-48E6-8E8B-2652FDB43B94Q34782190-B02DDEE1-72C2-437B-92CD-8F5291FCE5B8Q34998284-6F6FCD1B-1D11-4520-8DCB-40B6936543A8Q35002780-3335F290-32BA-456D-8474-491B2A9396E4Q35089685-7FD50DA5-8453-4E92-B3E3-FF834F9EE7D2Q35830494-32B0AC99-C086-459F-93CC-C692AA7D249FQ35984323-3968B767-2A40-48A4-A621-16C777E7199FQ36283334-0FB0EA98-1D7B-486D-A692-DF15251B2DB5Q36450027-361F9C6F-58B4-4819-89C8-446B76FDCD4FQ36513492-0DE10FF0-6568-44CA-A4F9-E9E92BD51927Q36514681-E1F72584-5100-4528-81D9-88ECB73E3E6FQ36696159-DA050407-1371-4298-A22A-4191A219E30FQ36836204-4142AD54-0E20-4AF2-83B6-C7AA57FD4B1BQ36854915-7BC4FA0F-1FCD-40E2-B988-38A6CC6A0275Q36956737-3AFE3FCA-9537-4ED0-B770-25BEE02E77E0Q37171218-54531DFE-C6C3-4B87-9AEA-DFB25B1FC964Q37225408-F05EA82E-5DB1-44C2-B872-6AC8200265D1Q37245963-D1A99D62-0372-4CA3-AD2F-70AE05AC4DA1Q37689977-6477F90F-B031-4BFA-8128-F716802E3014Q38884341-174CA878-F44E-42E3-9893-CC9097D37635Q39142308-C8B0BCE2-CDDB-4E9F-90C7-482CD79E68EDQ40544023-B127AD06-179F-4BD6-B023-730A9B668DEAQ41001492-D57C0D83-4BA9-43F4-9771-DD00306ECAA1Q52656382-C4238CA9-BDEF-4F24-A2B5-784CE3DBE391
P2860
Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: role of phosphorylation, protein trafficking, and regulatory factors.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Acute regulation of proximal t ...... cking, and regulatory factors.
@ast
Acute regulation of proximal t ...... cking, and regulatory factors.
@en
type
label
Acute regulation of proximal t ...... cking, and regulatory factors.
@ast
Acute regulation of proximal t ...... cking, and regulatory factors.
@en
prefLabel
Acute regulation of proximal t ...... cking, and regulatory factors.
@ast
Acute regulation of proximal t ...... cking, and regulatory factors.
@en
P1476
Acute regulation of proximal t ...... cking, and regulatory factors.
@en
P2093
P304
P577
1999-11-01T00:00:00Z