CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP
about
Arginine methyltransferases as novel therapeutic targets for breast cancerEstrogen Receptor α Is Required for Maintaining Baseline Renin Expression.Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating ElementEpigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancerMinireview: Tipping the balance: ligand-independent activation of steroid receptors.Meeting report: nuclear receptors: transcription factors and drug targets connecting basic research with translational medicine.The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer.Automethylation of CARM1 allows coupling of transcription and mRNA splicingThe histone modifications governing TFF1 transcription mediated by estrogen receptor.Sex-specific role for adenylyl cyclase type 7 in alcohol dependenceLiganded and unliganded activation of estrogen receptor and hormone replacement therapies.A role for estrogen receptor phosphorylation in the resistance to tamoxifen.Estrogen signaling and cardiovascular disease.Tetradian oscillation of estrogen receptor α is necessary to prevent liver lipid deposition.Endocrine resistance in breast cancer: from cellular signaling pathways to epigenetic mechanisms.Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity.Epigenetic regulation of estrogen signaling in breast cancerER and PR signaling nodes during mammary gland development.CARM1 automethylation is controlled at the level of alternative splicing.Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes.LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMPHistone arginine methylation.Role of PRMTs in cancer: Could minor isoforms be leaving a mark?Using unnatural amino acid mutagenesis to probe the regulation of PRMT1.Sex Drives Dimorphic Immune Responses to Viral Infections.O-GlcNAcylation of co-activator-associated arginine methyltransferase 1 regulates its protein substrate specificity.Estrogen and cigarette sidestream smoke particulate matter exhibit ERα-dependent tumor-promoting effects in lung adenocarcinoma cells.Roles of p21, p53, cyclin D1, CDK-4, estrogen receptor α in aflatoxin B1-induced cytotoxicity in testicular tissue of mice.The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis.The in vitro estrogenic activity of the crude drugs found in Japanese herbal medicines prescribed for menopausal syndrome was enhanced by combining them.CARM1 methylates MED12 to regulate its RNA-binding ability
P2860
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P2860
CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@ast
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@en
type
label
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@ast
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@en
prefLabel
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@ast
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@en
P2093
P2860
P356
P1433
P1476
CARM1 mediates the ligand-inde ...... strogen receptor alpha by cAMP
@en
P2093
Bruno Cenni
Didier Picard
Peter Dudek
Pierre-André Briand
Sophie Carascossa
P2860
P304
P356
10.1101/GAD.568410
P577
2010-04-01T00:00:00Z