Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. - Wikidata - awgldk - TriplyDB

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements.

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements.

http://www.wikidata.org/entity/Q33771214

about

Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited Cancer as a metabolic disease Targeting aspartate aminotransferase in breast cancer Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells A new view of carcinogenesis and an alternative approach to cancer therapy Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted Brick by brick: metabolism and tumor cell growth DNA Tumor Viruses and Cell Metabolism Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment Defining the metabolome: size, flux, and regulation The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer Antagonizing Bcl-2 family members sensitizes neuroblastoma and Ewing's sarcoma to an inhibitor of glutamine metabolism The role of Merkel cell polyomavirus and other human polyomaviruses in emerging hallmarks of cancer RAS oncogenes: weaving a tumorigenic web Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors Small molecules: the missing link in the central dogma Oxamate Improves Glycemic Control and Insulin Sensitivity via Inhibition of Tissue Lactate Production in db/db Mice Transcriptomic signature of bexarotene (rexinoid LGD1069) on mammary gland from three transgenic mouse mammary cancer models.Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines.Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation.Point mutations in c-Myc uncouple neoplastic transformation from multiple other phenotypes in rat fibroblasts Metabolic genes in cancer: their roles in tumor progression and clinical implications G protein-coupled receptors and the regulation of autophagy.Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect.Generalized theorems for nonlinear state space reconstruction.Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma.Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells.Perspective beyond cancer genomics: bioenergetics of cancer stem cells Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L)Three-dimensional multispecies nonlinear tumor growth-II: Tumor invasion and angiogenesis Differential behaviour of normal, transformed and Fanconi's anemia lymphoblastoid cells to modeled microgravity.Block copolymer micelles for controlled delivery of glycolytic enzyme inhibitors.Nonlinear modelling of cancer: bridging the gap between cells and tumours Cancer proliferation and therapy: the Warburg effect and quantum metabolism Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine.

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P2860

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements.

http://www.wikidata.org/entity/Q33771214

description

2005 nî lūn-bûn

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Stuart L Schreiber

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Cloning, characterization and mapping of the human ATP5E gene, identification of pseudogene ATP5EP1, and definition of the ATP5E motif

Creation of human tumour cells with defined genetic elements

Metabolite profiling for plant functional genomics

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

On respiratory impairment in cancer cells

Akt stimulates aerobic glycolysis in cancer cells

Glucose-induced stimulation of the Ras-cAMP pathway in yeast leads to multiple phosphorylations and activation of 6-phosphofructo-2-kinase.

A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth.

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.

Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells.

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