The role of T-cell receptor dimerization in T-cell activation.
about
T cell receptor engagement triggers its CD3epsilon and CD3zeta subunits to adopt a compact, locked conformationThe SCHOOL of nature: I. Transmembrane signaling.Calculations show substantial serial engagement of T cell receptors.Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody.The SCHOOL of nature: III. From mechanistic understanding to novel therapiesMembrane-mediated regulation of the intrinsically disordered CD3ϵ cytoplasmic tail of the TCR.T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytesLive-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.Translating the concept of suppressor/regulatory T cells to clinical applications.Class I MHC molecules as probes of membrane patchiness: from biophysical measurements to modulation of immune responses.Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms.Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation.Structural and functional identification of major histocompatibility complex class I-restricted self-peptides as naturally occurring molecular mimics of viral antigens. Possible role in CD8+ T cell-mediated, virus-induced autoimmune disease.Zinc binding and dimerization of Streptococcus pyogenes pyrogenic exotoxin C are not essential for T-cell stimulation.Cyclodimerization of immunosuppressive fragment of HLA-DR molecule. Design, synthesis and ESI-MS/MS analysis.
P2860
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P2860
The role of T-cell receptor dimerization in T-cell activation.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The role of T-cell receptor dimerization in T-cell activation.
@ast
The role of T-cell receptor dimerization in T-cell activation.
@en
type
label
The role of T-cell receptor dimerization in T-cell activation.
@ast
The role of T-cell receptor dimerization in T-cell activation.
@en
prefLabel
The role of T-cell receptor dimerization in T-cell activation.
@ast
The role of T-cell receptor dimerization in T-cell activation.
@en
P1433
P1476
The role of T-cell receptor dimerization in T-cell activation
@en
P2093
M F Bachmann
P304
P356
10.1016/S0167-5699(99)01543-1
P577
1999-12-01T00:00:00Z