about
Cancer classification using the Immunoscore: a worldwide task forceBcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closureDifferential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivoTowards the introduction of the 'Immunoscore' in the classification of malignant tumoursSevere impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infectionCbl-b is a negative regulator of receptor clustering and raft aggregation in T cellsGeneration and characterization of B7-H4/B7S1/B7x-deficient miceARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune systemICOS is essential for effective T-helper-cell responsesActivated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandDifferential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines.Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo.Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice.Selection of the T cell repertoire.Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damageExpansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs)The role of T-cell receptor dimerization in T-cell activation.Regulation of T cell activation, anxiety, and male aggression by RGS2.Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunityiRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSIRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV.Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.The sound of silence: modulating anergy in T lymphocytes.Making and breaking tolerance.Peptide-pulsed dendritic cells have superior ability to induce immune-mediated tissue destruction compared to peptide with adjuvantDeficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infectionThe E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infectionNatural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunityDefining the critical hurdles in cancer immunotherapy.Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunityORFV: a novel oncolytic and immune stimulating parapoxvirus therapeutic.TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes.Human CD4-major histocompatibility complex class II (DQw6) transgenic mice in an endogenous CD4/CD8-deficient background: reconstitution of phenotype and human-restricted function.Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicityProtein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Pamela S Ohashi
@ast
Pamela S Ohashi
@en
Pamela S Ohashi
@es
Pamela S Ohashi
@nl
type
label
Pamela S Ohashi
@ast
Pamela S Ohashi
@en
Pamela S Ohashi
@es
Pamela S Ohashi
@nl
prefLabel
Pamela S Ohashi
@ast
Pamela S Ohashi
@en
Pamela S Ohashi
@es
Pamela S Ohashi
@nl
P214
P106
P21
P214
P31
P496
0000-0003-2915-9317
P735
P7859
lccn-n93102207