Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins. - Wikidata - awgldk - TriplyDB

Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.

Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.

http://www.wikidata.org/entity/Q33780727

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Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals Molecular targets of TRAIL-sensitizing agents in colorectal cancer Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.Dihydroartemisinin enhances Apo2L/TRAIL-mediated apoptosis in pancreatic cancer cells via ROS-mediated up-regulation of death receptor 5 Snake venom toxin from Vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway.Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK High-throughput screen of natural product libraries for hsp90 inhibitors.Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers.Epigarcinol and isogarcinol isolated from the root of Garcinia ovalifolia induce apoptosis of human promyelocytic leukemia (HL-60 cells).(E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice.Low-dose anisomycin sensitizes melanoma cells to TRAIL induced apoptosis Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors.Carbenoxolone enhances TRAIL-induced apoptosis through the upregulation of death receptor 5 and inhibition of gap junction intercellular communication in human glioma.Prevention and Treatment of Colorectal Cancer by Natural Agents From Mother Nature.Updates on Antiobesity Effect of Garcinia Origin (-)-HCA.Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol.Garcinol regulates EMT and Wnt signaling pathways in vitro and in vivo, leading to anticancer activity against breast cancer cells.Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species.Chemical biology of histone acetyltransferase natural compounds modulators.Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells.Chemical composition, antioxidant, antitumor, anticancer and cytotoxic effects of Psidium guajava leaf extracts.Garcinol inhibits tumour cell proliferation, angiogenesis, cell cycle progression and induces apoptosis via NF-κB inhibition in oral cancer.Novel TRAIL sensitizer Taraxacum officinale F.H. Wigg enhances TRAIL-induced apoptosis in Huh7 cells.Garcinol and Its Role in Chronic Diseases.(E)-2,4-Bis(p-hydroxyphenyl)-2-butenal inhibits tumor growth via suppression of NF-κB and induction of death receptor 6.Snake venom toxin from Vipera lebetina turanica sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.Ethanol promotes cytotoxic effects of tumor necrosis factor-related apoptosis-inducing ligand through induction of reactive oxygen species in prostate cancer cells.Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling.Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.Potential role of garcinol as an anticancer agent.Gomisin N enhances TRAIL-induced apoptosis via reactive oxygen species-mediated up-regulation of death receptors 4 and 5 Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR).Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5.Ellagic acid inhibits proliferation and induces apoptosis in human glioblastoma cells.Terpenes from essential oils and hydrolate of triggered apoptotic events dependent on caspases activation and PARP cleavage in human colon cancer cells through decreased protein expressions Retraction: Garcinol Potentiates TRAIL-Induced Apoptosis through Modulation of Death Receptors and Antiapoptotic Proteins

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Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.

http://www.wikidata.org/entity/Q33780727

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

@ast

Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

@en

type

label

Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

@ast

Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

@en

prefLabel

Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

@ast

Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

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1535-7163.MCT-09-1113

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Molecular Cancer Therapeutics

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Garcinol potentiates TRAIL-ind ...... rs and antiapoptotic proteins.

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Bharat B Aggarwal

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Bokyung Sung

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Jayaraj Ravindran

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Manoj K Pandey

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Sahdeo Prasad

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P2860

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

The receptor for the cytotoxic ligand TRAIL

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.

Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis.

Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats.

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10.1158/1535-7163.MCT-09-1113

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4

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20371723

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2852472

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