Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats - Wikidata - awgldk - TriplyDB

Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats

Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats

http://www.wikidata.org/entity/Q33782221

about

Gene therapy for ischemic heart disease Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress?Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases Redox balance dynamically regulates vascular growth and remodeling Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling Prenatal exposure to lipopolysaccharide results in myocardial remodelling in adult murine offspring.Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.Glutaredoxin-1 overexpression enhances neovascularization and diminishes ventricular remodeling in chronic myocardial infarction.The protective effect of microRNA-320 on left ventricular remodeling after myocardial ischemia-reperfusion injury in the rat model.Modulation of signaling mechanisms in the heart by thioredoxin 1.The emerging role of the thioredoxin system in angiogenesis Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice.Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function.Xiaokening stimulates endothelial nitric oxide release in diabetic rats.Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice.Thioredoxin 1 enhances neovascularization and reduces ventricular remodeling during chronic myocardial infarction: a study using thioredoxin 1 transgenic mice Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging.Oxidative stress contributes to the impaired sonic hedgehog pathway in type 1 diabetic mice with myocardial infarction.Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.HECT-Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin-Interacting Protein and Ameliorates Reactive Oxygen Species-Induced Cardiotoxicity.PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion.A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis.Application of recombinant thioredoxin1 for treatment of heart disease.Oxidative stress in heart failure: what are we missing?Diabetes, oxidative stress, molecular mechanism, and cardiovascular disease--an overview.Cell stress proteins in atherothrombosis Interacting with thioredoxin-1--disease or no disease?Genetics and genomics of ischemic tolerance: focus on cardiac and cerebral ischemic preconditioning.Diabetic cardiomyopathy and its mechanisms: Role of oxidative stress and damage.Oxidative stress in severe acute illness.Thioredoxin superfamily and its effects on cardiac physiology and pathology.ROS signaling and redox biology in endothelial cells.Thioredoxins in cardiovascular disease.Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats.Trimodal rescue of hind limb ischemia with growth factors, cells, and nanocarriers: fundamentals to clinical trials.Epalrestat increases glutathione, thioredoxin, and heme oxygenase-1 by stimulating Nrf2 pathway in endothelial cells.Mechanistic Role of Thioredoxin 2 in Heart Failure.The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker?Protective effects of Phyllanthus emblica against myocardial ischemia-reperfusion injury: the role of PI3-kinase/glycogen synthase kinase 3β/β-catenin pathway.

P2860

Q24632135-285DD891-C893-4A69-BCBA-368D0B540FC1 Q26851362-FB18324A-2EB3-435C-ACA0-5E4AB38F40B2 Q27003070-D6BFE99E-CCE0-4BA9-AB44-79F5FB9E2CCD Q27004547-D5BFDBCD-2B12-4A4E-AA16-42C9DD7C8FDF Q28389739-02EA3A37-E6D2-4D19-B1F1-4628ADF9299C Q30445274-3892DC06-87B9-488B-80DE-D330182D156F Q30449821-092055A2-3D81-4DDC-B465-9E133C2FCABC Q34001695-28B60C5D-F285-4CE2-89A9-E2FDDD3FDA3A Q34241559-B51EFC44-0ACC-4F27-AF68-6D77C90A00E5 Q34486554-7A6B7B0E-710F-4580-92CB-9C472E4C7659 Q34547638-47F217F3-2FA0-4290-9DDA-34FC74FFD8B8 Q35123800-23A57922-67C9-45F8-B161-D1ECF1E0E391 Q35173596-FF1EC972-AD89-4070-B44B-3158AA3A9999 Q35217815-A0F9C14D-6A61-4423-A76C-DA5133B5FD90 Q35905038-C214D93F-D580-4DEF-8629-7B28A8A5B43E Q35922922-AEB87945-767B-4312-B5F2-58CD9B8AFF38 Q36096847-E6F57B54-0E5E-4338-8552-A446A049CA47 Q36112481-653E087D-C253-41CA-B9DD-B795A4E82927 Q36336214-1720EFED-3BB0-404F-BD4D-DABB3FDA8B5B Q36709361-80DE084A-4CA4-45F8-846A-84C9B576EC85 Q36877602-5B8E5E6D-720E-4987-B817-22ED4D85401C Q37325166-2CAE3359-1DAD-4B69-90F0-8A3503F7AC30 Q37510205-D00984A2-FC12-47AB-A161-8A51B9E8C99E Q37801029-6A51AA64-64A9-4425-97EE-53069CB161BD Q37900100-DFB1B778-1ACE-4C59-8C90-0B6FC2CE1765 Q37991017-4CC9798C-6085-4245-9F1D-A26D5E78D4F5 Q38026043-228787E8-D49D-4F12-BCA9-19A95F1EC4CF Q38032332-CF58FD99-68FF-4D52-BE1A-772F2EAC96B2 Q38061499-BFDE1C2B-1699-482A-BF50-8AE6E54DF210 Q38271210-5C63E8CE-6986-4DBE-87B9-D88E2E4B6B62 Q38341610-3D274CBD-28BB-41C4-9718-EEBE16856F2B Q38423835-9DB1C943-3A17-497C-BC11-4116780DB97B Q38478574-49E9FBAD-3658-4440-92D3-139C73ADD8DC Q38595062-4B9F66F3-C92C-421C-AD21-D16034B0C2FD Q38915485-4CC68F01-B947-4552-8AF2-5F28E8F9B5D0 Q39240834-E1A3DA1C-CD3B-472E-9C23-8A54D11AC186 Q43047088-E5A1D88D-812A-463C-A740-5DDF3B81A1D6 Q46359834-12C74C63-6FDA-40E1-BE3C-BB931B18A09F Q48256915-84E372DF-9147-4367-B950-8E117736B727 Q53355500-47167149-C79A-4BF4-8805-DE0A990A6C69

P2860

Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats

http://www.wikidata.org/entity/Q33782221

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@ast

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@en

type

label

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@ast

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@en

prefLabel

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@ast

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@en

P1433

Q33782221-2134E5BA-F9F5-43B2-BC98-500BD8EA410F

P1476

Q33782221-E4285415-CB55-4593-B694-968298286D2F

P2093

Q33782221-0771497A-9CDA-46A0-A442-8700B88C254B

Q33782221-56FF7631-C3D7-4AC8-928A-81484CF754F6

Q33782221-6050CA18-38BF-4733-9196-00E1A9C08D63

Q33782221-7F5DB7DF-C0C0-468B-BADE-F17307ADBB22

Q33782221-B0C470A0-B552-4E7F-AE57-26B1C70863F7

Q33782221-BB3C4D42-625E-41A2-934D-9AE902674828

Q33782221-BFC89488-BBF1-46B8-B379-9540A7877E2A

Q33782221-D4AA3C0B-37E0-4907-83E2-46653780F4D5

P2860

Q33782221-00FAB2DD-73C7-4486-B435-78BFB048356D

Q33782221-0D0FA62B-A05B-46AB-940C-59D056FD4710

Q33782221-0E5ECEE2-52A0-4F0A-BCA9-A85A7EA29B4B

Q33782221-1C756985-2C96-40D1-AD7E-CCE53EE4C7F0

Q33782221-1CA1751A-2E3A-4E3A-B8D0-5FB51BF228EB

Q33782221-1E50C95D-2A8C-4CA9-8852-3E2BF32D8304

Q33782221-31CD2013-68D3-412E-84D2-CC8B8286C7B4

Q33782221-37CB4B7E-EE87-46AD-8FFC-CC0D58CDD0BC

Q33782221-38B3AFF2-1102-476B-9AE2-2D5D0E967659

Q33782221-41555978-9EB0-4203-BD1B-357FD2717042

P304

Q33782221-719E5929-F0D2-494A-AC4E-AA83A8F750F8

P31

Q33782221-926F4B37-DD44-4518-BE61-E6821C4F2C7B

P356

Q33782221-330A31C8-D63F-406C-A5C1-CF35531085C2

P407

Q33782221-6A3288D7-EBAC-4F36-A728-89EF025B9A58

P433

Q33782221-296CABB5-7AFF-4BEB-9F1D-568747AB5DAD

P478

Q33782221-4AC16B4D-ECB2-426C-9603-98AFEFD6598E

P577

Q33782221-941844BE-962C-4B42-8E60-5837B3E7F98F

P698

Q33782221-8BBD91F9-E233-4288-A66B-B74B3E32250F

P921

Q33782221-8A84BDE7-5F02-42A5-A190-DFDE8E938F8B

P932

Q33782221-F5C3C832-A075-4FA1-8CCD-DE57B70751FE

P356

CIRCULATIONAHA.109.872481

P1433

P1476

Thioredoxin-1 gene therapy enh ...... ed myocardium of diabetic rats

@en

P2093

Gautam Maulik

http://www.w3.org/2001/XMLSchema#string

Lijun Zhan

http://www.w3.org/2001/XMLSchema#string

Mahesh Thirunavukkarasu

http://www.w3.org/2001/XMLSchema#string

Nilanjana Maulik

http://www.w3.org/2001/XMLSchema#string

Perumana R Sudhakaran

http://www.w3.org/2001/XMLSchema#string

Samson Mathews Samuel

http://www.w3.org/2001/XMLSchema#string

Srikanth Koneru

http://www.w3.org/2001/XMLSchema#string

Suresh Varma Penumathsa

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF.

Coadministration of adenoviral vascular endothelial growth factor and angiopoietin-1 enhances vascularization and reduces ventricular remodeling in the infarcted myocardium of type 1 diabetic rats.

Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion.

Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy.

Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62.

Thioredoxin1 upregulates mitochondrial proteins related to oxidative phosphorylation and TCA cycle in the heart.

Abnormal angiogenesis in diabetes mellitus.

Heme oxygenase-1: unleashing the protective properties of heme.

P304

1244-1255

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1161/CIRCULATIONAHA.109.872481

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

121

http://www.w3.org/2001/XMLSchema#string

P577

2010-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20194885

http://www.w3.org/2001/XMLSchema#string

P921

P932

2852871

http://www.w3.org/2001/XMLSchema#string