CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences - Wikidata - awgldk - TriplyDB

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

http://www.wikidata.org/entity/Q33791286

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Engineered Swine Models of Cancer Genome Engineering with TALE and CRISPR Systems in Neuroscience RNA Interference in the Age of CRISPR: Will CRISPR Interfere with RNAi?The therapeutic potential of genome editing for β-thalassemia Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Towards a new era in medicine: therapeutic genome editing How specific is CRISPR/Cas9 really?Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases Obesity genetics in mouse and human: back and forth, and back again Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9 Genetic screens and functional genomics using CRISPR/Cas9 technology Genome editing: the road of CRISPR/Cas9 from bench to clinic CRISPR guide RNA design for research applications Patterns of CRISPR/Cas9 activity in plants, animals and microbes Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens In vivo genome editing using Staphylococcus aureus Cas9 Cloning-free CRISPR A CRISPR view of development.CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites.GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.Optical Control of CRISPR/Cas9 Gene Editing.CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.Enhanced specificity and efficiency of the CRISPR/Cas9 system with optimized sgRNA parameters in Drosophila Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9 COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus).Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines Target specificity of the CRISPR-Cas9 system.Determining the specificities of TALENs, Cas9, and other genome-editing enzymes Landscape of target:guide homology effects on Cas9-mediated cleavage High-throughput functional genomics using CRISPR-Cas9.Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering Efficient Genome Editing in Clostridium cellulolyticum via CRISPR-Cas9 Nickase.Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9.Enhanced Rice Blast Resistance by CRISPR/Cas9-Targeted Mutagenesis of the ERF Transcription Factor Gene OsERF922.Genome Editing with CRISPR-Cas9: Can It Get Any Better?

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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

http://www.wikidata.org/entity/Q33791286

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2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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CRISPR/Cas9 systems have off-t ...... et DNA and guide RNA sequences

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CRISPR/Cas9 systems have off-t ...... et DNA and guide RNA sequences

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Nucleic Acids Research

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CRISPR/Cas9 systems have off-t ...... et DNA and guide RNA sequences

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Brian M Wile

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Frank J Stewart

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Gang Bao

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Harshavardhan Deshmukh

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Matthew T Brown

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Neha Sarode

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Paula M Vertino

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Piyush Ranjan

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Yanni Lin

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P2860

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Cas9 as a versatile tool for engineering biology

RNA-guided human genome engineering via Cas9

Multiplex genome engineering using CRISPR/Cas systems

Efficient genome editing in zebrafish using a CRISPR-Cas system

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

ENCODE data in the UCSC Genome Browser: year 5 update

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10.1093/NAR/GKU402

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11

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42

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Thomas J. Cradick

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2014-05-16T00:00:00Z

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262421062

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24838573

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4066799

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