Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts.
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Adeno-associated virus type 2-mediated gene transfer: role of cellular FKBP52 protein in transgene expressionMutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues.Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation.An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cellsOptimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblastsIntra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virusAAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients.High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapyEfficient generation and amplification of high-capacity adeno-associated virus/adenovirus hybrid vectors.Conjugate-based targeting of recombinant adeno-associated virus type 2 vectors by using avidin-linked ligands.Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.Adeno-associated virus type 2-mediated gene transfer: role of cellular T-cell protein tyrosine phosphatase in transgene expression in established cell lines in vitro and transgenic mice in vivo.AAV hybrid serotypes: improved vectors for gene deliveryOptimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?In vitro evaluation of a double-stranded self-complementary adeno-associated virus type2 vector in bone marrow stromal cells for bone healing.Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.Enhancement of recombinant adeno-associated virus type 2-mediated transgene expression in a lung epithelial cell line by inhibition of the epidermal growth factor receptorAAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects.Current status of gene therapy for inherited lung diseasesEnhancing gene delivery of adeno-associated viruses by cell-permeable peptidesUnique biologic properties of recombinant AAV1 transduction in polarized human airway epithelia.Species-specific differences in mouse and human airway epithelial biology of recombinant adeno-associated virus transduction.Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway.Gene therapy progress and prospects: recombinant adeno-associated virus (rAAV) vectors.Intracellular transport of recombinant adeno-associated virus vectors.Recombinant adeno-associated virus vectors for gene therapy.Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90Intracellular trafficking of adeno-associated viral vectors.Adeno-associated virus vectors: potential applications for cancer gene therapy.Precise hit: adeno-associated virus in gene targeting.Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In VivoDevelopment of optimized AAV3 serotype vectors: mechanism of high-efficiency transduction of human liver cancer cellsComplement is an essential component of the immune response to adeno-associated virus vectors.Distinct classes of proteasome-modulating agents cooperatively augment recombinant adeno-associated virus type 2 and type 5-mediated transduction from the apical surfaces of human airway epitheliaComparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer.Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses
P2860
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P2860
Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts.
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Impaired intracellular traffic ...... duction of murine fibroblasts.
@ast
Impaired intracellular traffic ...... duction of murine fibroblasts.
@en
type
label
Impaired intracellular traffic ...... duction of murine fibroblasts.
@ast
Impaired intracellular traffic ...... duction of murine fibroblasts.
@en
prefLabel
Impaired intracellular traffic ...... duction of murine fibroblasts.
@ast
Impaired intracellular traffic ...... duction of murine fibroblasts.
@en
P2093
P2860
P1433
P1476
Impaired intracellular traffic ...... duction of murine fibroblasts.
@en
P2093
P2860
P304
P356
10.1128/JVI.74.2.992-996.2000
P577
2000-01-01T00:00:00Z