The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expression
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Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways.Epstein-Barr virus SM protein interacts with mRNA in vivo and mediates a gene-specific increase in cytoplasmic mRNA.Attenuation of the suppressive activity of cellular splicing factor SRSF3 by Kaposi sarcoma-associated herpesvirus ORF57 protein is required for RNA splicingFunctional analysis of Epstein-Barr virus SM protein: identification of amino acids essential for structure, transactivation, splicing inhibition, and virion productionKaposi's sarcoma-associated herpesvirus lytic gene ORF57 is essential for infectious virion productionKaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppressionIdentification of the physiological gene targets of the essential lytic replicative Kaposi's sarcoma-associated herpesvirus ORF57 proteinSplit genes and their expression in Kaposi's sarcoma-associated herpesvirus.Gene structure and expression of Kaposi's sarcoma-associated herpesvirus ORF56, ORF57, ORF58, and ORF59.Stability of a long noncoding viral RNA depends on a 9-nt core element at the RNA 5' end to interact with viral ORF57 and cellular PABPC1.HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma-associated herpesvirus ORF57 protein and host pre-mRNA metabolismTargeted disruption of Kaposi's sarcoma-associated herpesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8alpha, and K8.1 and the production of infectious virus.Multiple roles of Epstein-Barr virus SM protein in lytic replication.Kaposi's sarcoma-associated herpesvirus ORF57 protein enhances mRNA accumulation independently of effects on nuclear RNA export.Binding of cellular export factor REF/Aly by Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is not required for efficient KSHV lytic replication.Promoter- and cell-specific transcriptional transactivation by the Kaposi's sarcoma-associated herpesvirus ORF57/Mta protein.Identification and Characterization of the Physiological Gene Targets of the Essential Lytic Replicative Epstein-Barr Virus SM Protein.Kaposi's sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing.Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.Extreme dependence of gH and gL expression on ORF57 and association with highly unusual codon usage in rhesus monkey rhadinovirusKaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.Cell-based screening assay for antiviral compounds targeting the ability of herpesvirus posttranscriptional regulatory proteins to stabilize viral mRNAs.Functional homology of gHs and gLs from EBV-related gamma-herpesviruses for EBV-induced membrane fusionKSHV Rta Promoter Specification and Viral Reactivation.Rhesus monkey rhadinovirus ORF57 induces gH and gL glycoprotein expression through posttranscriptional accumulation of target mRNAs.Kaposi's sarcoma-associated herpesvirus open reading frame 57 encodes a posttranscriptional regulator with multiple distinct activities.A single amino acid substitution in the ICP27 protein of herpes simplex virus type 1 is responsible for its resistance to leptomycin B.The Epstein-Barr virus SM protein is functionally similar to ICP27 from herpes simplex virus in viral infectionsIdentification of a lytic-cycle Epstein-Barr virus gene product that can regulate PKR activation.The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression.Protein kinase CK2 phosphorylation regulates the interaction of Kaposi's sarcoma-associated herpesvirus regulatory protein ORF57 with its multifunctional partner hnRNP K.The evolutionarily conserved Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with REF protein and acts as an RNA export factor.Alterations of mRNA splicing in primary effusion lymphomas.
P2860
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P2860
The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expression
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2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2000年の論文
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name
The human herpesvirus 8 homolo ...... l activator of gene expression
@ast
The human herpesvirus 8 homolo ...... l activator of gene expression
@en
type
label
The human herpesvirus 8 homolo ...... l activator of gene expression
@ast
The human herpesvirus 8 homolo ...... l activator of gene expression
@en
prefLabel
The human herpesvirus 8 homolo ...... l activator of gene expression
@ast
The human herpesvirus 8 homolo ...... l activator of gene expression
@en
P2093
P2860
P1433
P1476
The human herpesvirus 8 homolo ...... l activator of gene expression
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P2093
P2860
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P356
10.1128/JVI.74.2.1038-1044.2000
P577
2000-01-01T00:00:00Z