Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
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Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways.Caspase-7 cleavage of Kaposi sarcoma-associated herpesvirus ORF57 confers a cellular function against viral lytic gene expression.Number of and distance between response elements in Kaposi's sarcoma-associated herpesvirus ORF57 promoter influence its activation by replication and transcription activator and its repression by interferon regulatory factor 7.An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export.Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57.Attenuation of the suppressive activity of cellular splicing factor SRSF3 by Kaposi sarcoma-associated herpesvirus ORF57 protein is required for RNA splicingKaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.Kaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppressionMolecular biology of KSHV lytic reactivation.Stability of structured Kaposi's sarcoma-associated herpesvirus ORF57 protein is regulated by protein phosphorylation and homodimerization.Multiple regions of Kaposi's sarcoma-associated herpesvirus ORF59 RNA are required for its expression mediated by viral ORF57 and cellular RBM15.KSHV ORF57, a protein of many facesGammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX.HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma-associated herpesvirus ORF57 protein and host pre-mRNA metabolismKaposi's sarcoma-associated herpesvirus ORF57 is not a bona fide export factor.Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.NP1 Protein of the Bocaparvovirus Minute Virus of Canines Controls Access to the Viral Capsid Genes via Its Role in RNA Processing.Alternative RNA splicing of KSHV ORF57 produces two different RNA isoformsKSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features.The many roles of the highly interactive HSV protein ICP27, a key regulator of infection.KSHV Rta Promoter Specification and Viral Reactivation.Diverse virus-host interactions influence RNA-based regulation during γ-herpesvirus infection.Mutation of a C-terminal motif affects Kaposi's sarcoma-associated herpesvirus ORF57 RNA binding, nuclear trafficking, and multimerization.New insights into the expression and functions of the Kaposi's sarcoma-associated herpesvirus long noncoding PAN RNA.Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity.Viral factors reveal a role for REF/Aly in nuclear RNA stability.Chromatin immunoprecipitation and microarray analysis suggest functional cooperation between Kaposi's Sarcoma-associated herpesvirus ORF57 and K-bZIP.ORF57 overcomes the detrimental sequence bias of Kaposi's sarcoma-associated herpesvirus lytic genes.Restoring PU.1 induces apoptosis and modulates viral transactivation via interferon-stimulated genes in primary effusion lymphoma.CLIP-seq to Identify KSHV ORF57-Binding RNA in Host B Cells.KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation.
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P2860
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
@en
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
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type
label
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
@en
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
@nl
prefLabel
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
@en
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
@nl
P2860
P356
P1476
Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.
@en
P2093
Vladimir Majerciak
Zhi-Ming Zheng
P2860
P304
P356
10.2741/3322
P577
2009-01-01T00:00:00Z