Clustered charge-to-alanine mutagenesis of the vaccinia virus H5 gene: isolation of a dominant, temperature-sensitive mutant with a profound defect in morphogenesis
about
Vaccinia virus A30L protein is required for association of viral membranes with dense viroplasm to form immature virions.Members of a novel family of mammalian protein kinases complement the DNA-negative phenotype of a vaccinia virus ts mutant defective in the B1 kinaseIdentification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5RVaccinia Virus D4 Mutants Defective in Processive DNA Synthesis Retain Binding to A20 and DNAVaccinia virus L2 protein associates with the endoplasmic reticulum near the growing edge of crescent precursors of immature virions and stabilizes a subset of viral membrane proteinsVaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis.Vaccinia virus nonstructural protein encoded by the A11R gene is required for formation of the virion membrane.The vaccinia virus A9L gene encodes a membrane protein required for an early step in virion morphogenesis.Role of vaccinia virus A20R protein in DNA replication: construction and characterization of temperature-sensitive mutants.Regulation of viral intermediate gene expression by the vaccinia virus B1 protein kinase.Participation of vaccinia virus l2 protein in the formation of crescent membranes and immature virions.Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.Investigation of structural and functional motifs within the vaccinia virus A14 phosphoprotein, an essential component of the virion membrane.Existence of an operative pathway from the endoplasmic reticulum to the immature poxvirus membrane.Lipid membranes in poxvirus replication.CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1Molecular genetic and biochemical characterization of the vaccinia virus I3 protein, the replicative single-stranded DNA binding protein.Orthopoxvirus targets for the development of antiviral therapies.Biochemical and biophysical properties of a putative hub protein expressed by vaccinia virus.Vaccinia virus H7 protein contributes to the formation of crescent membrane precursors of immature virions.Cascade regulation of vaccinia virus gene expression is modulated by multistage promoters.Vaccinia virus mutants with alanine substitutions in the conserved G5R gene fail to initiate morphogenesis at the nonpermissive temperature.Viral serine/threonine protein kinasesMarker rescue mapping of the combined Condit/Dales collection of temperature-sensitive vaccinia virus mutants.Vaccinia Virus B1 Kinase Is Required for Postreplicative Stages of the Viral Life Cycle in a BAF-Independent Manner in U2OS Cells.Genetic Confirmation that the H5 Protein Is Required for Vaccinia Virus DNA Replication.Biogenesis of the vaccinia virus membrane: genetic and ultrastructural analysis of the contributions of the A14 and A17 proteins.Elucidating the essential role of the A14 phosphoprotein in vaccinia virus morphogenesis: construction and characterization of a tetracycline-inducible recombinant.Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.Charge cluster-to-alanine scanning of UL128 for fine tuning of the endothelial cell tropism of human cytomegalovirus.The vaccinia virus gene I2L encodes a membrane protein with an essential role in virion entry.Genetic analysis of the vaccinia virus I6 telomere-binding protein uncovers a key role in genome encapsidation.Vaccinia virus A6L encodes a virion core protein required for formation of mature virion.Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase.Genetic and cell biological characterization of the vaccinia virus A30 and G7 phosphoproteins.Cell biological and functional characterization of the vaccinia virus F10 kinase: implications for the mechanism of virion morphogenesisVaccinia virus A6 is essential for virion membrane biogenesis and localization of virion membrane proteins to sites of virion assemblyA targeted approach to identification of vaccinia virus postreplicative transcription elongation factors: genetic evidence for a role of the H5R gene in vaccinia transcription.Purification and properties of the vaccinia virus mRNA processing factor.
P2860
Q24529142-2F846AE2-529D-4C7A-9524-7C1B930DEBE5Q24607020-6CFB3E70-9FF5-421B-8919-015026097798Q24795211-BC69EB87-A0F8-4401-95B9-296F9DDE5210Q27664642-36E1A502-801D-4E3B-A764-251A7F53CE07Q28743094-436A9DA6-EFC1-42CA-B3C8-D636E94FAFE6Q33632176-EB74ECE3-D0FC-47EB-9F85-022A8705145BQ33770781-A80DB5E0-F524-4C53-A4FF-8E08B3A0DBE3Q33788819-CE0ACFBA-967E-4B61-9381-12B08FA5F0DEQ33811821-315EC772-D4E9-4FFA-91B6-6A92488FE148Q33837263-B957BD3D-8191-4E8A-BF3B-EBC26A0F16C4Q33839103-2FD21FB4-A631-43F8-A86B-2CAF7B49820DQ34742862-E4CD8D45-3C55-4B21-8F71-29D54047EE19Q35163548-C8C6ABE9-8A98-47FD-8DA2-41AB65D39F3CQ35182365-B5A8AC9D-F140-467E-868F-B006FADAF7D4Q35193307-D4B491BA-D55F-4880-8331-2F5A6BCED052Q35260919-0F3430ED-2C75-456C-A2D0-ACE5147FE766Q35784676-4F39E56A-8448-4185-8D11-546FC4558C60Q36023195-16A4D9AA-F046-47DC-9952-FA6FB0C73BC3Q36074391-ED44A25D-448C-4D0B-9935-28B2E4E5E180Q36779657-20D3E48B-D6C3-445B-B2F5-244A255941C7Q37333780-CCD72FE2-E5AE-4D0E-AF92-01844D39E2B3Q37341397-EDE8A21F-6807-4BB4-AE06-5A7756DB17C7Q37511614-0A08D32B-83E4-41EE-BC5A-D8746855CBAEQ37810382-09138842-C427-4DE4-976D-2870BF74C23DQ38632202-5780C4C9-763C-4F34-81DD-E2F8940EEC60Q38848079-59722C84-3A66-4844-85AB-19BD9EB5435AQ38889483-21FBBE47-70F0-472C-B977-D9806364F4ACQ39248073-1AFCDD51-CBF8-4ED8-B237-AE1882521870Q39590521-87BC679E-BA47-4DEE-844B-29C168FD52C8Q39611232-884B5E05-5F99-49ED-81FB-12515E5FB632Q39943786-8938E66D-A9A1-47A2-9CA5-AF83391B29F3Q39950913-8191C656-D1DF-4289-9A2E-C8794CA8F475Q39997681-6667E7D9-317A-4815-BE86-0037276774F4Q40208151-8663E2FB-6215-4E02-B10D-59364E7281B0Q40344000-AA56BB9F-05E3-4EEA-95DD-A3E952A89CEAQ40423204-B9803ADE-207C-4EEB-A933-DC4B725C70E6Q40463770-A179E373-D4DB-4A9C-8DCE-A74D9D8ECE17Q42122764-4942EB6D-356C-4CC3-BDCB-908625FB8CFAQ42132409-2FE5B374-B992-4749-A73C-456FB09ED34FQ44296374-DBBCD934-BB32-4D55-A7A3-169CADDFE3EE
P2860
Clustered charge-to-alanine mutagenesis of the vaccinia virus H5 gene: isolation of a dominant, temperature-sensitive mutant with a profound defect in morphogenesis
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@ast
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@en
type
label
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@ast
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@en
prefLabel
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@ast
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@en
P2860
P1433
P1476
Clustered charge-to-alanine mu ...... ofound defect in morphogenesis
@en
P2093
P Traktman
P2860
P304
P356
10.1128/JVI.74.5.2393-2405.2000
P50
P577
2000-03-01T00:00:00Z