Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.
about
Mitochondria and the autophagy-inflammation-cell death axis in organismal agingAutophagy modulation as a potential therapeutic target for diverse diseasesFBG1 Is the Final Arbitrator of A1AT-Z DegradationProcessing of optineurin in neuronal cellsAutophagy-based unconventional secretory pathway for extracellular delivery of IL-1βSpermidine protects against α-synuclein neurotoxicity.Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbancesEpigenetic deregulation in pediatric acute lymphoblastic leukemia.Crohn's disease: NOD2, autophagy and ER stress converge.Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice.Autophagy-regulating small molecules and their therapeutic applications.A curated census of autophagy-modulating proteins and small molecules: candidate targets for cancer therapy.Pharmacological regulators of autophagy and their link with modulators of lupus diseaseTargets for future clinical trials in Huntington's disease: what's in the pipeline?Analysis of proteolytic processes and enzymatic activities in the generation of huntingtin n-terminal fragments in an HEK293 cell model.Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells.Atg4b-dependent autophagic flux alleviates Huntington's disease progressionRegulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules.The contribution of lysosomotropism to autophagy perturbation.The generation of neutrophils in the bone marrow is controlled by autophagyMedical management of Parkinson's disease: focus on neuroprotectionThe toxicity of tau in Alzheimer disease: turnover, targets and potential therapeuticsAutophagy and cartilage homeostasis mechanisms in joint health, aging and OAEpigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic fluxAlzheimer's disease: pathological mechanisms and recent insights.Defining and measuring autophagosome flux—concept and realityEthambutol induces impaired autophagic flux and apoptosis in the rat retina.ER stress inhibits neuronal death by promoting autophagyModulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose.Lysosomal adaptation: How cells respond to lysosomotropic compounds.Rapamycin induces autophagy in the melanoma cell line M14 via regulation of the expression levels of Bcl-2 and Bax.Role of Carbonyl Modifications on Aging-Associated Protein Aggregation.Autophagy: regulation and role in developmentInduction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulationCarbamazepine as a novel small molecule corrector of trafficking-impaired ATP-sensitive potassium channels identified in congenital hyperinsulinism.Management of multicellular senescence and oxidative stress.A triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells.Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicityOnjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells.
P2860
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P2860
Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Chemical inducers of autophagy ...... in neurodegenerative diseases.
@ast
Chemical inducers of autophagy ...... in neurodegenerative diseases.
@en
type
label
Chemical inducers of autophagy ...... in neurodegenerative diseases.
@ast
Chemical inducers of autophagy ...... in neurodegenerative diseases.
@en
prefLabel
Chemical inducers of autophagy ...... in neurodegenerative diseases.
@ast
Chemical inducers of autophagy ...... in neurodegenerative diseases.
@en
P2860
P921
P356
P1476
Chemical inducers of autophagy ...... in neurodegenerative diseases
@en
P2093
David C Rubinsztein
Maurizio Renna
P2860
P304
11061-11067
P356
10.1074/JBC.R109.072181
P407
P5008
P577
2010-02-10T00:00:00Z