Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
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Alphavirus RNA synthesis and non-structural protein functionsDifferences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest VirusDissecting the Role of E2 Protein Domains in Alphavirus PathogenicityStructural and Nonstructural Protein Genome Regions of Eastern Equine Encephalitis Virus Are Determinants of Interferon Sensitivity and Murine VirulenceThe nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in miceThe Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding PocketADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulenceSH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replicationElimination of phosphorylation sites of Semliki Forest virus replicase protein nsP3.Intravenously administered alphavirus vector VA7 eradicates orthotopic human glioma xenografts in nude mice.Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region.Identification of adult mouse neurovirulence determinants of the Sindbis virus strain AR86.A single amino acid change in the nuclear localization sequence of the nsP2 protein affects the neurovirulence of Semliki Forest virus.Differential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growthPolyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.Alphavirus vectors as tools in cancer gene therapy.Recombinant sindbis/Venezuelan equine encephalitis virus is highly attenuated and immunogenic.Alphaviral cytotoxicity and its implication in vector development.MicroRNA-Attenuated Clone of Virulent Semliki Forest Virus Overcomes Antiviral Type I Interferon in Resistant Mouse CT-2A Glioma.Versatility of gene therapy vectors through viruses.Interferon-β sensitivity of tumor cells correlates with poor response to VA7 virotherapy in mouse glioma models.An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis.Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2.Improved Semliki Forest virus vectors for receptor research and gene therapy.Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model.Nonstructural Proteins of Alphavirus-Potential Targets for Drug Development.The Enigmatic Alphavirus Non-Structural Protein 3 (nsP3) Revealing Its Secrets at Last.Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases.The Pathogenesis of Alphaviruses
P2860
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P2860
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
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2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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name
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
@ast
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
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type
label
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
@ast
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
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prefLabel
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
@ast
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
@en
P2093
P2860
P1433
P1476
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence
@en
P2093
A E Hinkkanen
J A Määttä
M G Santagati
M T Tuittila
P2860
P304
P356
10.1128/JVI.74.10.4579-4589.2000
P577
2000-05-01T00:00:00Z