Patchwork pattern of transcriptional reactivation in the lungs indicates sequential checkpoints in the transition from murine cytomegalovirus latency to recurrence
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Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.Elimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell cultureMurine model of interstitial cytomegalovirus pneumonia in syngeneic bone marrow transplantation: persistence of protective pulmonary CD8-T-cell infiltrates after clearance of acute infection.Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungsThe major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth.Allogeneic transplantation induces expression of cytomegalovirus immediate-early genes in vivo: a model for reactivation from latencySystemic hematogenous maintenance of memory inflation by MCMV infection.Random, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalovirus latency in the lungs.Human Cytomegalovirus Latency: Approaching the Gordian Knot.Polycomb repressive complex 2 targets murine cytomegalovirus chromatin for modification and associates with viral replication centers.Persisting murine cytomegalovirus can reactivate and has unique transcriptional activity in ocular tissue.Viral escape mechanisms--escapology taught by viruses.Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion.Murine cytomegalovirus immediate-early 1 gene expression correlates with increased GVHD after allogeneic hematopoietic cell transplantation in recipients reactivating from latent infection.Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients.An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis.Lipopolysaccharide, tumor necrosis factor alpha, or interleukin-1beta triggers reactivation of latent cytomegalovirus in immunocompetent miceCD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivationMast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.Reversal of human cytomegalovirus major immediate-early enhancer/promoter silencing in quiescently infected cells via the cyclic AMP signaling pathway.Immediate-Early (IE) gene regulation of cytomegalovirus: IE1- and pp71-mediated viral strategies against cellular defensesMemory T cells specific for murine cytomegalovirus re-emerge after multiple challenges and recapitulate immunity in various adoptive transfer scenarios.Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro.Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response.Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance.Sepsis and cytomegalovirus: foes or conspirators?Liver sinusoidal endothelial cells are a site of murine cytomegalovirus latency and reactivationImmune evasion proteins enhance cytomegalovirus latency in the lungs.Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs.Tissue-specific control of latent CMV reactivation by regulatory T cells.Cytomegalovirus and immunotherapy: opportunistic pathogen, novel target for cancer and a promising vaccine vector.The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF-{kappa}B sites during acute infectionRecognition of a novel stage of betaherpesvirus latency in human herpesvirus 6Known unknowns: how might the persistent herpesvirome shape immunity and aging?IL-10 restricts memory T cell inflation during cytomegalovirus infection.The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene ProductsDeep sequencing reveals highly complex dynamics of human cytomegalovirus genotypes in transplant patients over time.Murine cytomegalovirus major immediate-early protein 3 interacts with cellular and viral proteins in viral DNA replication compartments and is important for early gene activationThe loss of binary: Pushing the herpesvirus latency paradigm.
P2860
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P2860
Patchwork pattern of transcriptional reactivation in the lungs indicates sequential checkpoints in the transition from murine cytomegalovirus latency to recurrence
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@ast
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@en
type
label
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@ast
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@en
prefLabel
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@ast
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@en
P2860
P1433
P1476
Patchwork pattern of transcrip ...... alovirus latency to recurrence
@en
P2093
M J Reddehase
P2860
P304
P577
1999-10-01T00:00:00Z