Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.
about
Axl is essential for VEGF-A-dependent activation of PI3K/AktExpression of lysophosphatidic acid, autotaxin and acylglycerol kinase as biomarkers in diabetic retinopathy.Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosisMT-MMPS as Regulators of Vessel Stability Associated with AngiogenesisInsulin-like growth factor 1 (IGF-1) stabilizes nascent blood vesselsAutotaxin overexpression causes embryonic lethality and vascular defectsDiabetes disrupts the response of retinal endothelial cells to the angiomodulator lysophosphatidic acidLysophosphatidic acid causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells.MEF2C ablation in endothelial cells reduces retinal vessel loss and suppresses pathologic retinal neovascularization in oxygen-induced retinopathyPrimary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA).Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progressionControlling cancer through the autotaxin-lysophosphatidic acid receptor axis.Regression activity that is naturally present in vitreous becomes ineffective as patients develop proliferative diabetic retinopathyLactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis.Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis.Human periprostatic adipose tissue promotes prostate cancer aggressiveness in vitro.Analysing calcium dependent and independent regulation of eNOS in endothelium triggered by extracellular signalling events.Expression of autotaxin and acylglycerol kinase in proliferative vitreoretinal epiretinal membranes.
P2860
Q28116976-A6847C51-36AE-41BA-A70B-54B0EF2AF283Q34292377-01A4F971-1EFC-473D-B30F-0753BEC3E237Q34660049-61A235D3-04A2-4EAB-9B92-B9ADB9DDBDFEQ35025845-D8EF8606-1FFE-4E02-993D-F7D6C754B9E5Q35172962-6AF76173-D12E-442D-9E35-65AE727E6DF8Q35625325-CE44E21B-33E1-4D18-9901-3B8BED332632Q35902906-4F675C7F-F947-434F-9DE3-C6CE7B88E84FQ35907288-CB863B69-3D96-47FB-AA54-C3EB2470B208Q36044670-1943DBE1-A9E2-47E7-95D4-7E028642E8DDQ36083085-998B2E50-C405-4051-8123-19B868F71DDDQ36399256-36F357B4-59A1-4486-9110-456EF002CDB9Q36664243-5B803666-0083-4A16-AE22-8085CB22F0C1Q37098594-9623B747-C4CE-4E40-8150-A6E68FE31350Q37175153-87C908F1-B667-4E78-86AE-7982F45E7F89Q37620329-CCEA73B8-4952-42B0-9427-2C92DB188698Q42209269-E4320CBB-71B7-479A-8A61-57E65F71FECCQ42443326-3B9668F8-4A63-421A-806D-E692F64D4524Q54548435-D101F222-302E-4466-B004-D9B7733CB88B
P2860
Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phospholipase Cgamma activatio ...... dic acid-dependent regression.
@ast
Phospholipase Cgamma activatio ...... dic acid-dependent regression.
@en
type
label
Phospholipase Cgamma activatio ...... dic acid-dependent regression.
@ast
Phospholipase Cgamma activatio ...... dic acid-dependent regression.
@en
prefLabel
Phospholipase Cgamma activatio ...... dic acid-dependent regression.
@ast
Phospholipase Cgamma activatio ...... dic acid-dependent regression.
@en
P2093
P2860
P356
P1476
Phospholipase Cgamma activatio ...... idic acid-dependent regression
@en
P2093
Andrius Kazlauskas
Eun Young Park
Jorge Aranda
Lorenzo Federico
Mary L Stracke
Ruta Motiejunaite
Susan Smyth
Timothy Clair
P2860
P304
P356
10.1128/MCB.01275-09
P407
P50
P577
2010-03-15T00:00:00Z