Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
about
Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibitionChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageCheckpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex.Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response.Cell cycle proteins as promising targets in cancer therapyDefective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.Mammary tumor phenotypes in wild-type aging female FVB/N mice with pituitary prolactinomas.
P2860
Q28396027-9862BCC6-B284-4C2E-AD9F-DA338BD95D5BQ28511458-42D229C0-5F51-4B53-86E4-87CBF5F162B1Q36170865-BDAC4518-1569-4A87-AD3E-4D43B936F171Q37386101-68B5F2BA-85BA-4A88-9C20-BC261526EB4BQ37497709-F0CAE1C0-9210-40C7-83DF-6A4D017A616AQ37693690-530DB0EC-E2A2-4953-A946-118D8C937769Q40244137-953E7A8E-70B2-45DB-9620-B2E599BE4773Q44130924-3C244FBD-4556-4BA8-9E0F-C11E0ED41015
P2860
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
description
2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@ast
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@en
type
label
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@ast
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@en
prefLabel
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@ast
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@en
P2093
P2860
P1433
P1476
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.
@en
P2093
Daniel A Haber
Emmett V Schmidt
Eunice L Kwak
Jianmin Zhang
Robert D Cardiff
P2860
P304
P356
10.1158/0008-5472.CAN-05-1237
P407
P577
2006-02-01T00:00:00Z