hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
about
A systematic review of the cardiotoxicity of methadonemicroRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessmentComputer-based prediction of the drug proarrhythmic effect: problems, issues, known and suspected challengesMulti-Organ toxicity demonstration in a functional human in vitro system composed of four organs.Bayesian quantitative electrophysiology and its multiple applications in bioengineering.Selective serotonin reuptake inhibitors and torsade de pointes: new concepts and new directions derived from a systematic review of case reportsNovel Bayesian classification models for predicting compounds blocking hERG potassium channels.Antipsychotics and torsadogenic risk: signals emerging from the US FDA Adverse Event Reporting System database.A chemogenomic analysis of ionization constants--implications for drug discoveryInvestigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay.A k-nearest neighbor classification of hERG K(+) channel blockers.Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem.Chemical-protein interactome and its application in off-target identification.The significance of acid/base properties in drug discoveryStem cells and stem cell-derived tissues and their use in safety assessment.Lubiprostone: pharmacokinetic, pharmacodynamic, safety and regulatory aspects in the treatment of constipation-predominant irritable bowel syndrome.Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitorsEvidence for the hERG Liability of Antihistamines, Antipsychotics, and Anti-Infective Agents: A Systematic Literature Review From the ARITMO Project.Predicting in vivo safety characteristics using physiochemical properties and in vitro assays.Multiple Kernel Learning for Drug Discovery.Structural insight into the transmembrane segments 3 and 4 of the hERG potassium channelIn Silico ADME/Tox PredictionsExperimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities
P2860
Q26766513-741FE8F9-C694-4475-9D47-31A7EEB17880Q26778918-495A784A-F9B4-414E-AB43-68061DE2B75BQ26861453-87613A4D-5E67-4A42-AFC2-E4042B0D8F5AQ27300308-CA3A2A50-25AB-4CB7-A27E-546FE68AB616Q30442585-99FD74AB-4D99-4551-8B71-0F2B2FF0F7D1Q34016220-3DB27EF7-2EDF-4918-AD9F-AB0735B50470Q34017962-4813DCBE-A242-462B-BD54-5DCBDC360A35Q34336897-1B7A77D9-3601-4173-BE45-43BCE1058E27Q34543267-98DC7EE8-7E6D-4F41-933C-20B1FC5D0796Q35883599-D6D6EE2E-50A1-4E5F-B269-FEE844F3AEF7Q35918516-AC2DD837-5317-4764-81CA-C1E7C39F5B86Q37248049-D5D83765-AAB7-4FCB-B4D1-698C66BCFA4FQ37849214-4DD8D0D4-8702-4BC0-94A3-AAE70B8B4FF2Q38055676-8CF0DA50-935B-4893-81EF-50E5E0CD0B5FQ38173227-672F97A2-F544-4E24-A4AA-1B4F028510DBQ38175457-299A7CF8-214E-4D62-9B47-E1B08314C537Q38732067-E935C27B-39DD-424E-A3D4-AAFD7C4508F8Q39055260-8A2B39B4-C765-4CDE-BFE6-9894AF0B21BAQ39481089-F49E2ACF-C029-41AE-8A11-42CA892B7905Q39540349-93441484-3FC6-4C70-8DD3-85C4A4A3F792Q56898136-537705DC-A306-4D2E-BE7B-F0372D14393DQ56984194-DB972D3B-2563-42BC-99D7-9AC2EFA3E1B6Q58553697-1D7AFFC2-7465-4127-AAD0-245359673F44
P2860
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@ast
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@en
type
label
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@ast
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@en
prefLabel
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@ast
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@en
P2860
P1476
hERG-related drug toxicity and models for predicting hERG liability and QT prolongation.
@en
P2093
Luisa Ceccarini
Maurizio Recanatini
P2860
P304
P356
10.1517/17425250903055070
P407
P577
2009-09-01T00:00:00Z