Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line - Wikidata - awgldk - TriplyDB

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

http://www.wikidata.org/entity/Q33848287

about

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease Alzheimer mechanisms and therapeutic strategies Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy AR, apoE, and cognitive function Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease Expression in vitro of alternatively spliced variants of the messenger RNA for human apolipoprotein E receptor-2 identified in human tissues by ribonuclease protection assays Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth Neuronal clearance of amyloid-β by endocytic receptor LRP1.Small-molecule structure correctors target abnormal protein structure and function: structure corrector rescue of apolipoprotein E4-associated neuropathology Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.Amyloid and lipids in the pathology of Alzheimer disease.Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice.APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein.LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis.Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo.APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease.Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.Reconstitution of the olfactory epithelium following injury in apoE-deficient mice.The role of apolipoprotein E in Alzheimer's disease.Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.Apolipoprotein E in synaptic plasticity and Alzheimer's disease: potential cellular and molecular mechanisms.Neuroplasticity in Alzheimer's disease.A quantitative proteomic approach to prion disease biomarker research: delving into the glycoproteome.Apolipoprotein E isoform-dependent dendritic recovery of hippocampal neurons following activation of innate immunity.The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors Central nervous system lipoproteins in Alzheimer's disease A role for apoE in regulating the levels of alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease.The distribution of apolipoprotein E in mouse olfactory epithelium Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord.Pivotal role of RanBP9 in integrin-dependent focal adhesion signaling and assembly.Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells LRP and Alzheimer's disease.

P2860

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P2860

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

http://www.wikidata.org/entity/Q33848287

description

1995 nî lūn-bûn

@nan

1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1995年の論文

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1995年論文

@yue

1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

@zh-mo

1995年論文

@zh-tw

1995年论文

@wuu

name

Low density lipoprotein recept ...... tem-derived neuronal cell line

@ast

Low density lipoprotein recept ...... tem-derived neuronal cell line

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type

label

Low density lipoprotein recept ...... tem-derived neuronal cell line

@ast

Low density lipoprotein recept ...... tem-derived neuronal cell line

@en

prefLabel

Low density lipoprotein recept ...... tem-derived neuronal cell line

@ast

Low density lipoprotein recept ...... tem-derived neuronal cell line

@en

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PNAS.92.21.9480

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Low density lipoprotein recept ...... tem-derived neuronal cell line

@en

P2093

A L Schwartz

http://www.w3.org/2001/XMLSchema#string

B Nathan

http://www.w3.org/2001/XMLSchema#string

D M Holtzman

http://www.w3.org/2001/XMLSchema#string

G Bu

http://www.w3.org/2001/XMLSchema#string

J Kilbridge

http://www.w3.org/2001/XMLSchema#string

R E Pitas

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R W Mahley

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P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor

Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

A receptor-mediated pathway for cholesterol homeostasis

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9480-9484

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scholarly article

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21

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92

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1995-10-01T00:00:00Z

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7568158

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