The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein.
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Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseTrafficking regulation of proteins in Alzheimer's diseaseGenetic structure characterization of Chileans reflects historical immigration patternsIdentification of LRP1B-interacting proteins and inhibition of protein kinase Calpha-phosphorylation of LRP1B by association with PICK1Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration.The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.Genetic or epigenetic silencing of low density lipoprotein receptor-related protein 1B expression in oral squamous cell carcinoma.gamma-Secretase-mediated release of the low density lipoprotein receptor-related protein 1B intracellular domain suppresses anchorage-independent growth of neuroglioma cells.Coronary artery aneurysms occurrence risk analysis between Kawasaki disease and LRP1B gene in Taiwanese children.Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.Using passenger mutations to estimate the timing of driver mutations and identify mutator alterationsAssociation between Variants in Atopy-Related Immunologic Candidate Genes and Pancreatic Cancer Risk.Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.Severe intellectual disability, omphalocele, hypospadia and high blood pressure associated to a deletion at 2q22.1q22.3: case report.LRP and Alzheimer's disease.A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI networkLipoprotein receptors--an evolutionarily ancient multifunctional receptor family.C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-β neurotoxicity.Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic EnvironmentGenome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer's disease in Caribbean Hispanic individualsAng II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice.The familial counterparts of follicular cell--derived thyroid tumors.Characteristics of the level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1.The role of lipoprotein receptors on the physiological function of APP.Lipoprotein receptor binding, cellular uptake, and lysosomal delivery of fusions between the receptor-associated protein (RAP) and alpha-L-iduronidase or acid alpha-glucosidase.Characterization of a low-density lipoprotein receptor, Lrp13, in Chinese tongue sole (Cynoglossus semilaevis) and medaka (Oryzias latipes).Functional Roles of the Interaction of APP and Lipoprotein Receptors.Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells.The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.The low density lipoprotein receptor-related protein modulates protease activity in the brain by mediating the cellular internalization of both neuroserpin and neuroserpin-tissue-type plasminogen activator complexes.Common Expression Quantitative Trait Loci Shared by Histone Genes.LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE-carrying lipoproteins.Expression of a recombinant full-length LRP1B receptor in human non-small cell lung cancer cells confirms the postulated growth-suppressing function of this large LDL receptor family member.Two novel deletions (array CGH findings) in pigment dispersion syndrome.Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.Decreased expression of the low-density lipoprotein receptor-related protein-1 (LRP-1) in rats with prostate cancer.Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations
P2860
Q24336718-36D3CD30-FA1E-4F08-A17A-A1BA4496D705Q24604376-6150B5BE-FBDE-4AC3-865C-6E15F02242BEQ24650450-0206E410-CD99-492C-B2EE-74CA605FF2A5Q26825722-71574452-A7BB-4B9D-A57E-EAAAE2FAE47CQ28314937-F18FDEE0-55B0-4DF6-BA8D-6D08DDDD55ACQ28509380-4A48DAC0-8349-4215-BB04-4BEBCB5C5687Q34145983-B54681B7-48C1-4D95-AF82-204CC86512B9Q34318694-F7497C1A-1214-424F-B5A2-272A0C675C27Q34558676-803213A5-DA01-469D-B043-00AB0E197AE3Q34602706-4BECCF13-2986-4757-988B-6968EED1CD50Q34691843-C7900082-4CC9-4B51-B2EB-430443392CD9Q35023109-845736BD-D3D3-4578-8417-762BE18210F8Q35065185-7A72D18B-B055-4C65-B51A-A60F8687B7CAQ35577056-4F0D3BAA-DC8A-4606-B052-F4B8AC475C40Q36029702-8A078873-A72E-4988-8687-A83DADFBC8DEQ36125601-CC7EC901-A2F4-4B86-A1C4-394430090631Q36164972-D2AEF6A5-6492-4A51-83AB-CDBCB6FCF2C5Q36255013-CF9220FB-87BF-4211-AA02-9D3EFC541641Q36486210-B7D3AA15-725E-4BCE-B021-C6DFD169D103Q36508752-092CD7C7-2102-4710-8668-71677F1EF87BQ36548865-59007C72-8A3C-4522-8C61-77118D37E1FEQ36618909-DE59E88E-3620-44D4-88EA-13C0C8B962A0Q36749726-CD1D72BC-F855-4405-AF4F-FF34A98829A7Q37742941-A735F416-AE0C-437B-98C8-6A67C5B4A35FQ37801943-E63866E2-D790-43D0-AD34-351CE432E285Q37938682-04FCF41D-0D2B-45DD-8011-34C528F104C2Q38340653-180D6FDD-25F5-4943-B8A9-FD136B514A08Q38652270-3DDE3FE4-4D3B-45A0-A92C-BF641567C8AAQ39180867-3309737E-8F3D-46E8-A785-E10BE365ACE6Q39634789-92DE12C2-E4B3-4535-9B5B-10DDF4FFDEFBQ40571781-B71E5487-8342-488F-9728-39E6371B4F2BQ40629527-0F9D757E-2C79-44AD-9E4D-2CA1AEA529BAQ41449838-AB3FD033-E5CD-46B4-8E6E-2E2CEAC874B8Q41973219-D6929012-3304-4453-AA58-088432B7F631Q42315536-65140CFB-9ED5-446E-8500-0132733EB8A1Q46831456-8B83F8D2-36D4-4773-B38F-32AB27D9928CQ46903589-C09BD247-8F35-4E94-A58D-01B5C8332DD8Q47592174-DEC1FC83-E5A0-4051-830F-6F109895E826Q52097635-C454D029-F67E-4CFA-ABF8-CE934ACD9508Q58122651-A1CF1966-E226-4A7B-A4C5-32441103475F
P2860
The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The putative tumor suppressor ...... LDL receptor-related protein.
@ast
The putative tumor suppressor ...... LDL receptor-related protein.
@en
type
label
The putative tumor suppressor ...... LDL receptor-related protein.
@ast
The putative tumor suppressor ...... LDL receptor-related protein.
@en
prefLabel
The putative tumor suppressor ...... LDL receptor-related protein.
@ast
The putative tumor suppressor ...... LDL receptor-related protein.
@en
P2093
P2860
P356
P1476
The putative tumor suppressor ...... LDL receptor-related protein.
@en
P2093
Obermoeller-McCormick LM
Schwartz AL
P2860
P304
28889-28896
P356
10.1074/JBC.M102727200
P407
P577
2001-05-30T00:00:00Z