AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha.

AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha.

Item
http://www.wikidata.org/entity/Q33851189
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cellsThe human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activityHerpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein.Functional interaction between fluorodeoxyuridine-induced cellular alterations and replication of a ribonucleotide reductase-negative herpes simplex virus.Up to four distinct polypeptides are produced from the γ34.5 open reading frame of herpes simplex virus 2Signals that dictate nuclear, nucleolar, and cytoplasmic shuttling of the gamma(1)34.5 protein of herpes simplex virus type 1Differential reliance on autophagy for protection from HSV encephalitis between newborns and adultsICP34.5 protein of herpes simplex virus facilitates the initiation of protein translation by bridging eukaryotic initiation factor 2alpha (eIF2alpha) and protein phosphatase 1Replication of herpes simplex virus 1 depends on the gamma 134.5 functions that facilitate virus response to interferon and egress in the different stages of productive infection.The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR.The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus-Host Interactions.HSV targeting of the host phosphatase PP1α is required for disseminated disease in the neonate and contributes to pathogenesis in the brain.Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication.Dephosphorylation of eIF2alpha mediated by the gamma134.5 protein of herpes simplex virus 1 facilitates viral neuroinvasionVirus-induced ER stress and the unfolded protein responseAn N-terminal arginine-rich cluster and a proline-alanine-threonine repeat region determine the cellular localization of the herpes simplex virus type 1 ICP34.5 protein and its ligand, protein phosphatase 1.
P2860

AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha.

Item
http://www.wikidata.org/entity/Q33851189
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@ast
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@en
type
label
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@ast
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@en
prefLabel
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@ast
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932
P356
P1433
P1476
AlaArg motif in the carboxyl t ...... t dephosphorylates eIF-2alpha.
@en
P2093
P2860
P304
P31
P356
10.1128/JVI.75.8.3666-3674.2001
P433
P478
P577
P698
P932