Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4
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Architecture and secondary structure of an entire HIV-1 RNA genomeDifferential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNRMolecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structureWest Nile Virus Discriminates between DC-SIGN and DC-SIGNR for Cellular Attachment and InfectionCorrelation of acute humoral response with brain virus burden and survival time in pig-tailed macaques infected with the neurovirulent simian immunodeficiency virus SIVsmmFGbElectron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions.Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.Interaction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolateStructure and dynamics of the HIV-1 frameshift element RNAInfluence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS modelAdoption of an "open" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques.Distinct molecular pathways to X4 tropism for a V3-truncated human immunodeficiency virus type 1 lead to differential coreceptor interactions and sensitivity to a CXCR4 antagonist.Neutralizing antibody responses in recent seroconverters with HIV-1 subtype C infections in India.Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic.Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challengeDiversity of envelope genes from an uncloned stock of SIVmac251.An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data.Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virusTCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infectionEvidence for antibody-mediated enhancement of simian immunodeficiency virus (SIV) Gag antigen processing and cross presentation in SIV-infected rhesus macaquesImportance of B-cell responses for immunological control of variant strains of simian immunodeficiency virus.Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs.Autologous aldrithiol-2-inactivated HIV-1 combined with polyinosinic-polycytidylic acid-poly-L-lysine carboxymethylcellulose as a vaccine platform for therapeutic dendritic cell immunotherapyAn alteration of human immunodeficiency virus gp41 leads to reduced CCR5 dependence and CD4 independence.Variations in the Biological Functions of HIV-1 Clade C Envelope in a SHIV-Infected Rhesus Macaque during Disease Progression.Unique pattern of convergent envelope evolution in simian immunodeficiency virus-infected rapid progressor macaques: association with CD4-independent usage of CCR5.Expression of simian immunodeficiency virus (SIV) nef in astrocytes during acute and terminal infection and requirement of nef for optimal replication of neurovirulent SIV in vitro.Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system.Cell tropism of simian immunodeficiency virus in culture is not predictive of in vivo tropism or pathogenesisCharacterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.CD4-independent use of the CCR5 receptor by sequential primary SIVsm isolatesInduction of antibody-mediated neutralization in SIVmac239 by a naturally acquired V3 mutation.Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.Although macrophage-tropic simian/human immunodeficiency viruses can exhibit a range of pathogenic phenotypes, a majority of isolates induce no clinical disease in immunocompetent macaques.Analysis of SIVmac Envelope-Specific Antibodies Selected Through Phage Display.Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.CD45 immunoaffinity depletion of vesicles from Jurkat T cells demonstrates that exosomes contain CD45: no evidence for a distinct exosome/HIV-1 budding pathway.CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo.A single amino acid change and truncated TM are sufficient for simian immunodeficiency virus to enter cells using CCR5 in a CD4-independent pathway.Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections.
P2860
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P2860
Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@ast
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@en
type
label
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@ast
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@en
prefLabel
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@ast
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@en
P2093
P2860
P1433
P1476
Ability of the V3 loop of simi ...... nd decreased dependence on CD4
@en
P2093
R C Desrosiers
T Matthews
P2860
P304
P356
10.1128/JVI.75.8.3903-3915.2001
P577
2001-04-01T00:00:00Z