Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
about
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblastsA nuclear target for interleukin-1alpha: interaction with the growth suppressor necdin modulates proliferation and collagen expressionRole of platelet-derived growth factors in physiology and medicineEmerging targets for the treatment of scleroderma.The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts.RNA interference against platelet-derived growth factor receptor α mRNA inhibits fibroblast transdifferentiation in skin lesions of patients with systemic sclerosis.CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouseApoptosis modulation as a promising target for treatment of systemic sclerosis.Tocilizumab for the treatment of rheumatoid arthritis and other systemic autoimmune diseases: current perspectives and future directions.Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferationEffect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts.The Trypanosoma cruzi trans-sialidase, through its COOH-terminal tandem repeat, upregulates interleukin 6 secretion in normal human intestinal microvascular endothelial cells and peripheral blood mononuclear cellsThe precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription.Mechanisms of Disease: the role of immune cells in the pathogenesis of systemic sclerosis.Update on pathophysiology of scleroderma with special reference to immunoinflammatory events.Tocilizumab for the treatment of steroid refractory graft-versus-host disease.Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network.Interleukin 1α and the inflammatory process.Biomarkers for skin involvement and fibrotic activity in scleroderma.Immunotherapeutic implication of IL-6 blockade.T cells in systemic sclerosis: a reappraisal.Interleukin-6: a new therapeutic target in systemic sclerosis?Current frontiers in systemic sclerosis pathogenesis.HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarminsAssociation of interleukin 1 family with systemic sclerosis.Elevated serum levels of interleukin-1β and interleukin-33 in patients with systemic sclerosis in Chinese population.Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis.Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis?Astrocytes attenuate oligodendrocyte death in vitro through an alpha(6) integrin-laminin-dependent mechanism.Serum nitric oxide (NO) levels in systemic sclerosis patients: correlation between NO levels and clinical features.The IL - 6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis.Function and regulation of IL-1α in inflammatory diseases and cancer.Sarcoidosis and Systemic Sclerosis: Strange Bedfellows.Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis.Tocilizumab reduced production of systemic sclerosis-related autoantibodies and anti-cyclic citrullinated protein antibodies in two patients with overlapping systemic sclerosis and rheumatoid arthritis.Angiopoietin-like protein 2 promotes inflammatory conditions in the ligamentum flavum in the pathogenesis of lumbar spinal canal stenosis by activating interleukin-6 expression.
P2860
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P2860
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@ast
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@en
type
label
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@ast
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@en
prefLabel
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@ast
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@en
P2093
P2860
P356
P1476
Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.
@en
P2093
P2860
P304
P356
10.1172/JCI4304
P407
P577
1999-05-01T00:00:00Z