Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase.

Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase.

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http://www.wikidata.org/entity/Q33858358
Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analoguesBinding of 3,4,5,6-Tetrahydroxyazepanes to the Acid-β-glucosidase Active Site: Implications for Pharmacological Chaperone Design for Gaucher DiseaseNeuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds.Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease.Glucocerebrosidase inhibitors for the treatment of Gaucher disease.sp2-Iminosugar O-, S-, and N-glycosides as conformational mimics of α-linked disaccharides; implications for glycosidase inhibition.Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases.Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase ModulatorsNew Directions in Gaucher Disease.Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.Structural basis of pharmacological chaperoning for human β-galactosidase.A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.
P2860

Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase.

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http://www.wikidata.org/entity/Q33858358
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@ast
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@en
type
label
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@ast
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@en
prefLabel
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@ast
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Bicyclic (galacto)nojirimycin ...... towards β-glucocerebrosidase.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921