DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
about
Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismMTH1 as a Chemotherapeutic Target: The Elephant in the Room.Accumulation of abasic sites induces genomic instability in normal human gastric epithelial cells during Helicobacter pylori infection.Naturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease.ATM prevents DSB formation by coordinating SSB repair and cell cycle progression.Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stressBiological effects of novel "combi-targeting" molecule and its effect on DNA repair pathway in hormone-refractory prostate cancerMutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint.Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaksLoss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway.A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis.Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability.Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapyKinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2.PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation.Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2Onset of deaminase APOBEC3B induction in response to DNA double-strand breaks
P2860
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P2860
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@ast
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@en
type
label
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@ast
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@en
prefLabel
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@ast
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@en
P2093
P2860
P356
P1476
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
@en
P2093
Bernd Kaina
Christian Ebel
Lucie Iloff
Markus Lӧbrich
Michael Ensminger
Teodora Nikolova
P2860
P356
10.1083/JCB.201312078
P407
P577
2014-06-30T00:00:00Z