Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
about
Keeping mtDNA in shape between generationsChanges in Regenerative Capacity through LifespanMitochondrial DNA damage patterns and aging: revising the evidences for humans and miceSomatic mutations in aging, cancer and neurodegenerationHigh-throughput sequencing in mitochondrial DNA researchMitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and agingOxidative stress is not a major contributor to somatic mitochondrial DNA mutationsMitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old CharactersParkinson's disease as a result of agingThe hallmarks of agingAccumulation of DNA damage in the aged hematopoietic stem cell compartmentIL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genomeVariegated expression of Hsp22 transgenic reporters indicates cell-specific patterns of aging in Drosophila oenocytesFinding the lost treasures in exome sequencing data.Mitochondria sequence mapping strategies and practicability of mitochondria variant detection from exome and RNA sequencing data.Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic functionTargeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain.Mitochondrial genome maintenance in health and disease.Transmission from centenarians to their offspring of mtDNA heteroplasmy revealed by ultra-deep sequencing.Animal Mitochondrial DNA as We Do Not Know It: mt-Genome Organization and Evolution in Nonbilaterian Lineages.Replication pauses of the wild-type and mutant mitochondrial DNA polymerase gamma: a simulation study.Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing.Maternally transmitted mitochondrial DNA mutations can reduce lifespanMitoBreak: the mitochondrial DNA breakpoints database.Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila.Selection for Mitochondrial Quality Drives Evolution of the Germline.Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions.Lessons learned from implementing a national infrastructure in Sweden for storage and analysis of next-generation sequencing data.Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damageMitochondrial DNA mutations in disease and agingMathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance.Human stem cell aging: do mitochondrial DNA mutations have a causal role?Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA.Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion.Mitochondrial maintenance failure in aging and role of sexual dimorphism.Organelle DNA rearrangement mapping reveals U-turn-like inversions as a major source of genomic instability in Arabidopsis and humans.Comparison of mice with accelerated aging caused by distinct mechanismsVisualization of mitochondrial respiratory function using cytochrome c oxidase/succinate dehydrogenase (COX/SDH) double-labeling histochemistry.mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling.
P2860
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P2860
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@ast
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@en
type
label
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@ast
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@en
prefLabel
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@ast
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@en
P2860
P50
P1433
P1476
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
@en
P2093
Erik Hagström
Max Ingman
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002028
P577
2011-03-24T00:00:00Z