Do mtDNA deletions drive premature aging in mtDNA mutator mice?
about
MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevityΑlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's DiseaseAddressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging.Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.Mitochondrial DNA alterations and reduced mitochondrial function in agingSimilar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humansAssociation of G-quadruplex forming sequences with human mtDNA deletion breakpoints.Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions.Mitochondrial DNA mutations in disease and agingPost-translational decrease in respiratory chain proteins in the Polg mutator mouse brain.The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimersAge-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria.Animal models of mitochondrial DNA transactions in disease and ageingMetabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brainThe role of DNA exonucleases in protecting genome stability and their impact on ageing.Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence.The exonuclease activity of the yeast mitochondrial DNA polymerase γ suppresses mitochondrial DNA deletions between short direct repeats in Saccharomyces cerevisiaeRunning on empty: does mitochondrial DNA mutation limit replicative lifespan in yeast?: Mutations that increase the division rate of cells lacking mitochondrial DNA also extend replicative lifespan in Saccharomyces cerevisiae.The pathology roadmap in Parkinson disease.Mitochondrial function and mitochondrial DNA maintenance with advancing age.Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases.Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis.Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury
P2860
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P2860
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
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2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
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2009年論文
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2009年論文
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2009年论文
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Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@ast
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@en
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@nl
type
label
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@ast
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@en
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@nl
prefLabel
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@ast
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@en
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@nl
P2093
P2860
P1433
P1476
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
@en
P2093
David K Simon
Douglas M Turnbull
Konstantin Khrapko
Yevgenya Kraytsberg
P2860
P356
10.1111/J.1474-9726.2009.00484.X
P407
P577
2009-08-01T00:00:00Z