Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.
about
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalEGF receptor is required for KRAS-induced pancreatic tumorigenesisCo-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC.A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cellsJunD/AP-1-mediated gene expression promotes lymphocyte growth dependent on interleukin-7 signal transduction.Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growthProtein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanismErlotinib-cisplatin combination inhibits growth and angiogenesis through c-MYC and HIF-1α in EGFR-mutated lung cancer in vitro and in vivo.Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer.The nuclear epidermal growth factor receptor signaling network and its role in cancer.Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways.DEspR roles in tumor vasculo-angiogenesis, invasiveness, CSC-survival and anoikis resistance: a 'common receptor coordinator' paradigm.STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway.STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.
P2860
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P2860
Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@ast
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@en
type
label
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@ast
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@en
prefLabel
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@ast
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@en
P2093
P2860
P356
P1476
Enhanced sensitivity of pancre ...... growth factor receptor or Src.
@en
P2093
James Turkson
Peibin Yue
Soumya Jaganathan
P2860
P304
P356
10.1124/JPET.109.162669
P407
P577
2010-01-25T00:00:00Z