Quantifying the kinetic parameters of prion replication.
about
The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseaseMeasurement of amyloid formation by turbidity assay-seeing through the cloudPrion diseases: dynamics of the infection and properties of the bistable transition.Early efforts in modeling the incubation period of infectious diseases with an acute course of illness.Investigating the conformational stability of prion strains through a kinetic replication model.Prion dynamics and the quest for the genetic determinant in protein-only inheritanceThere is no safe dose of prions.Theoretical modeling of prion disease incubation.Simulations of oligomeric intermediates in prion diseases.Autocatalytic self-propagation of misfolded prion proteinThe prion hypothesis: from biological anomaly to basic regulatory mechanism.The molecular pathology of CJD: old and new variants.An efficient kinetic model for assemblies of amyloid fibrils and its application to polyglutamine aggregation.The most infectious prion protein particles.Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation.Interactions between Aβ and mutated Tau lead to polymorphism and induce aggregation of Aβ-mutated tau oligomeric complexesQuaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics.Characterization of the nanoscale properties of individual amyloid fibrilsInsights into prion biology: integrating a protein misfolding pathway with its cellular environment.A micellar on-pathway intermediate step explains the kinetics of prion amyloid formationDistinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo.Molecular dynamics simulations of alanine rich beta-sheet oligomers: Insight into amyloid formation.Conformational propagation with prion-like characteristics in a simple model of protein foldingComputational modeling of the relationship between amyloid and disease.Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein.A mathematical model of the dynamics of prion aggregates with chaperone-mediated fragmentationStructural fingerprints and their evolution during oligomeric vs. oligomer-free amyloid fibril growthChemical and biophysical insights into the propagation of prion strains.Mapping the parameters of prion-induced neuropathology.Prion propagation: the role of protein dynamicsPolymorphism of fibrillar structures depending on the size of assembled Aβ17-42 peptides.Divergent prion strain evolution driven by PrPC expression level in transgenic mice.Exploring the topological sources of robustness against invasion in biological and technological networksGeneration of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome.Kinetics of prion growth.Sampling the self-assembly pathways of KFFE hexamers.The length distribution of frangible biofilaments.Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations.
P2860
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P2860
Quantifying the kinetic parameters of prion replication.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Quantifying the kinetic parameters of prion replication.
@ast
Quantifying the kinetic parameters of prion replication.
@en
type
label
Quantifying the kinetic parameters of prion replication.
@ast
Quantifying the kinetic parameters of prion replication.
@en
prefLabel
Quantifying the kinetic parameters of prion replication.
@ast
Quantifying the kinetic parameters of prion replication.
@en
P1476
Quantifying the kinetic parameters of prion replication
@en
P2093
P304
P356
10.1016/S0301-4622(99)00016-2
P577
1999-03-01T00:00:00Z