The prion hypothesis: from biological anomaly to basic regulatory mechanism.
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MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune responseIs tau ready for admission to the prion club?Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseActin, Membrane Trafficking and the Control of Prion Induction, Propagation and Transmission in YeastDisaggregases, molecular chaperones that resolubilize protein aggregatesPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersPrion-like polymerization as a signaling mechanismThe [RNQ+] prion: a model of both functional and pathological amyloidProbing the role of structural features of mouse PrP in yeast by expression as Sup35-PrP fusionsMolecular epigenetic switches in neurodevelopment in health and diseaseEngineering enhanced protein disaggregases for neurodegenerative diseaseLoss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein foldingAmyloid-associated activity contributes to the severity and toxicity of a prion phenotypeA yeast prion, Mod5, promotes acquired drug resistance and cell survival under environmental stressHeritable yeast prions have a highly organized three-dimensional architecture with interfiber structures.Prions, amyloids, and RNA: Pieces of a puzzle.Yeast prions assembly and propagation: contributions of the prion and non-prion moieties and the nature of assemblies.PASTA 2.0: an improved server for protein aggregation prediction.[KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis.Prion propagation can occur in a prokaryote and requires the ClpB chaperone.Genomic clustering and homology between HET-S and the NWD2 STAND protein in various fungal genomesAltered Prion protein expression pattern in CSF as a biomarker for Creutzfeldt-Jakob disease.The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.Environmental regulation of prions in yeast.De novo genome assembly of the soil-borne fungus and tomato pathogen Pyrenochaeta lycopersici.Defining the limits: Protein aggregation and toxicity in vivoSpatial quality control bypasses cell-based limitations on proteostasis to promote prion curing.Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation.Insights into prion biology: integrating a protein misfolding pathway with its cellular environment.Functional diversification of hsp40: distinct j-protein functional requirements for two prions allow for chaperone-dependent prion selectionExpanding the rule set of DNA circuitry with associative toehold activationPrion protein at the crossroads of physiology and disease.EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells.Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo.Self-assembly of peptide boroxoles on cis-dihydroxylated oligoamide templates in water.Generating extracellular amyloid aggregates using E. coli cells.A mathematical model of the dynamics of prion aggregates with chaperone-mediated fragmentationHeat shock protein (Hsp) 70 is an activator of the Hsp104 motor.Exploring the basis of [PIN(+)] variant differences in [PSI(+)] inductionLaboratory activities involving transmissible spongiform encephalopathy causing agents: risk assessment and biosafety recommendations in Belgium.
P2860
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P2860
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@ast
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@en
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@nl
type
label
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@ast
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@en
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@nl
prefLabel
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@ast
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@en
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@nl
P2860
P356
P1476
The prion hypothesis: from biological anomaly to basic regulatory mechanism.
@en
P2093
Mick F Tuite
Tricia R Serio
P2860
P2888
P304
P356
10.1038/NRM3007
P577
2010-11-17T00:00:00Z
P5875
P6179
1009567465