Expression of Fatty Acid Synthase Depends on NAC1 and Is Associated with Recurrent Ovarian Serous Carcinomas
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Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft modelFatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration.FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and GUp-regulated FASN expression promotes transcoelomic metastasis of ovarian cancer cell through epithelial-mesenchymal transitionAmplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinomaOverexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis.Tumor cell metabolism: an integral view.Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer.Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas.NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells.Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study.Aberrant lipid metabolism: an emerging diagnostic and therapeutic target in ovarian cancer.Fatty acid synthase is a potential therapeutic target in estrogen receptor-/progesterone receptor-positive endometrioid endometrial cancer.Metabolic Regulation of Apoptosis in Cancer.Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies.Nucleus accumbens-associated protein-1 promotes glycolysis and survival of hypoxic tumor cells via the HDAC4-HIF-1α axis.The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas.Development of a novel ovarian cancer molecular target therapy against cancer-related transcriptional factor, NAC1.Silencing of NAC1 Expression Induces Cancer Cells Oxidative Stress in Hypoxia and Potentiates the Therapeutic Activity of Elesclomol.A QM/MM study of the reaction mechanism of human β-ketoacyl reductase.Fatty acid synthase (FASN) as a therapeutic target in breast cancer.One-Carbon Metabolism: Biological Players in Epithelial Ovarian Cancer
P2860
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P2860
Expression of Fatty Acid Synthase Depends on NAC1 and Is Associated with Recurrent Ovarian Serous Carcinomas
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@ast
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@en
type
label
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@ast
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@en
prefLabel
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@ast
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@en
P2093
P2860
P356
P1433
P1476
Expression of Fatty Acid Synth ...... rent Ovarian Serous Carcinomas
@en
P2093
Ben Davidson
Francis P Kuhajda
Ie-Ming Shih
Kai Lee Yap
Kala Visvanathan
Robert E Bristow
Stefanie M Ueda
Tian-Li Wang
Vivek Murthy
P2860
P304
P356
10.1155/2010/285191
P577
2010-05-19T00:00:00Z