The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas.
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Metabolomics in rheumatic diseases: desperately seeking biomarkersA novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosisA novel human leiomyoma tissue derived matrix for cell culture studies.Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of AssaysCancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.Blocking fatty acid synthase inhibits tumor progression of human osteosarcoma by regulating the human epidermal growth factor receptor 2/phosphoinositide 3-kinase/protein kinase B signaling pathway in xenograft modelsFatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration.The selective target of capsaicin on FASN expression and de novo fatty acid synthesis mediated through ROS generation triggers apoptosis in HepG2 cells.Subcutaneous adipocytes promote melanoma cell growth by activating the Akt signaling pathway: role of palmitic acidCandidate biomarker discovery for angiogenesis by automatic integration of Orbitrap MS1 spectral- and X!Tandem MS2 sequencing informationMacrophage-tumor cell fusions from peripheral blood of melanoma patientsMetformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193bQuantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome.Regulation of lipid synthesis by the RNA helicase Mov10 controls Wnt5a production.Development of a Self-Assembled Nanoparticle Formulation of Orlistat, Nano-ORL, with Increased Cytotoxicity against Human Tumor Cell Lines.Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.FASN expression, angiogenesis and lymphangiogenesis in central and peripheral giant cell lesions.Metabolism of stromal and immune cells in health and disease.Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model.Inhibition of fatty acid synthase suppresses neovascularization via regulating the expression of VEGF-A in glioma.Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respirationObesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: role of adipokines.Metformin treatment reduces temozolomide resistance of glioblastoma cells.An Overview of Lipid Droplets in Cancer and Cancer Stem Cells.Total synthesis of tetrahydrolipstatin and stereoisomers via a highly regio- and diastereoselective carbonylation of epoxyhomoallylic alcohols."Stealth dissemination" of macrophage-tumor cell fusions cultured from blood of patients with pancreatic ductal adenocarcinoma.Fatty acid synthase as a potential therapeutic target in feline oral squamous cell carcinoma.Mechanistic Study of Bakuchiol-Induced Anti-breast Cancer Stem Cell and in Vivo Anti-metastasis Effects.Hypoxia Pathway Proteins As Central Mediators of Metabolism in the Tumor Cells and Their Microenvironment.Fatty acid synthase (FASN) as a therapeutic target in breast cancer.High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.Adipophilin expression in cutaneous malignant melanoma.Obesity and Cancer: Existing and New Hypotheses for a Causal Connection.Metabolic Enzymes in Sarcomagenesis: Progress Toward Biology and Therapy.p53 and metabolism: from mechanism to therapeutics.Cancer cell metabolism as new targets for novel designed therapiesThe contributions of cancer cell metabolism to metastasis
P2860
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P2860
The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@en
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@nl
type
label
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@en
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@nl
prefLabel
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@en
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@nl
P2093
P2860
P356
P1476
The fatty acid synthase inhibi ...... ogenesis in B16-F10 melanomas.
@en
P2093
A M Chudzinski-Tavassi
D C Bastos
K G Zecchin
M A Carvalho
M Agostini
M P Alvarez-Flores
R D Coletta
P2860
P2888
P304
P356
10.1038/BJC.2012.355
P407
P577
2012-08-14T00:00:00Z