Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.
about
Identification of a proline-rich Akt substrate as a 14-3-3 binding partnerThe PI3K-PDK1 connection: more than just a road to PKBRegulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating AktAkt kinases in breast cancer and the results of adjuvant therapyDeficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic micePhosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?Saposin C promotes survival and prevents apoptosis via PI3K/Akt-dependent pathway in prostate cancer cellsAkt2: a role in breast cancer metastasisEnhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.The critical role of Akt in cardiovascular functionPhosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistanceDifferences between human breast cell lines in susceptibility towards growth inhibition by genisteinDownregulation of Akt1 inhibits anchorage-independent cell growth and induces apoptosis in cancer cellsPI3K/PTEN signaling in angiogenesis and tumorigenesisOxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer CellsRegulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesAll Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.Downregulation of miR-31, miR-155, and miR-564 in chronic myeloid leukemia cellsLigand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells.Discovery of a novel class of AKT pleckstrin homology domain inhibitors.Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.Transcriptional repression by RB-E2F and regulation of anchorage-independent survival.Akt2 inhibition enables the forkhead transcription factor FoxO3a to have a repressive role in estrogen receptor alpha transcriptional activity in breast cancer cells.Akt inhibitors: mechanism of action and implications for anticancer therapeutics.Non-peptidic substrate-mimetic inhibitors of Akt as potential anti-cancer agents.Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing.The PI3K-Akt-mTOR pathway in initiation and progression of thyroid tumors.Associations between clinicopathological prognostic factors and pAkt, pMAPK and topoisomerase II expression in breast cancer.Novel inhibitors of AKT: assessment of a different approach targeting the pleckstrin homology domain.Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo.AKT plays a central role in tumorigenesis.Sequence analysis of mutations and translocations across breast cancer subtypesIn vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.Caffeic acid phenethyl ester causes p21 induction, Akt signaling reduction, and growth inhibition in PC-3 human prostate cancer cells.Rhodopsin-regulated insulin receptor signaling pathway in rod photoreceptor neurons.Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer.Akt/protein kinase B promotes organ growth in transgenic mice.Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.The class I PI3K/Akt pathway is critical for cancer cell survival in dogs and offers an opportunity for therapeutic intervention
P2860
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P2860
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Up-regulation of Akt3 in estro ...... pendent prostate cancer lines.
@ast
Up-regulation of Akt3 in estro ...... pendent prostate cancer lines.
@en
type
label
Up-regulation of Akt3 in estro ...... pendent prostate cancer lines.
@ast
Up-regulation of Akt3 in estro ...... pendent prostate cancer lines.
@en
prefLabel
Up-regulation of Akt3 in estro ...... pendent prostate cancer lines.
@ast
Up-regulation of Akt3 in estro ...... pendent prostate cancer lines.
@en
P2093
P2860
P356
P1476
Up-regulation of Akt3 in estro ...... ependent prostate cancer lines
@en
P2093
P2860
P304
21528-21532
P356
10.1074/JBC.274.31.21528
P407
P577
1999-07-01T00:00:00Z