Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
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Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injuryDysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testisExploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissueGeneration and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts.Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growthSPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT.Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progressionFunctional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.A functional variant in the MTOR promoter modulates its expression and is associated with renal cell cancer riskFunctional analysis of Tcl1 using Tcl1-deficient mouse embryonic stem cells.AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradationGlucose metabolism measured by [¹⁸F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells.Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT modelAltered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alphaOncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells.Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric CancerRole of IkappaB kinase in tumorigenesis.Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]An immunohistochemical perspective of PPAR beta and one of its putative targets PDK1 in normal ovaries, benign and malignant ovarian tumours.PTEN, more than the AKT pathway.Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer.Phosphatase and tensin homologue deleted on chromosome 10The PLK1 inhibitor GSK461364A is effective in poorly differentiated and anaplastic thyroid carcinoma cells, independent of the nature of their driver mutationsA PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylationAkt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiencyA systems biology view of cancerDeletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction.Genetic aberrations and survival in plasma cell leukemiaThe Role of PTEN in β-Cell Growth.Signals controlling un-differentiated states in embryonic stem and cancer cells: role of the phosphatidylinositol 3' kinase pathway.MiR-92a Promotes Cell Metastasis of Colorectal Cancer Through PTEN-Mediated PI3K/AKT Pathway.PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis.Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice.Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling.Expression of Akt (protein kinase B) and its isoforms in malignant lymphomas.Increased expression of Mcl-1 is required for protection against serum starvation in phosphatase and tensin homologue on chromosome 10 null mouse embryonic fibroblasts, but repression of Bim is favored in human glioblastomas.The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion.
P2860
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P2860
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@ast
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@en
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@nl
type
label
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@ast
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@en
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@nl
prefLabel
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@ast
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@en
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@nl
P2093
P2860
P1476
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.
@en
P2093
Bangyan Stiles
Natalya Khanzenzon
Ralf Lesche
Valeriya Gilman
P2860
P304
P356
10.1128/MCB.22.11.3842-3851.2002
P407
P577
2002-06-01T00:00:00Z