Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity. - Wikidata - awgldk - TriplyDB

Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity.

Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity.

http://www.wikidata.org/entity/Q33870401

about

Preventing the transmission of American trypanosomiasis and its spread into non-endemic countries Ruthenium complex with benznidazole and nitric oxide as a new candidate for the treatment of chagas disease Pathogenesis of chagas' disease: parasite persistence and autoimmunity Challenges and perspectives of Chagas disease: a review.New drugs for neglected infectious diseases: Chagas' disease.In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease.Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death Glyceraldehyde 3-phosphate dehydrogenase-telomere association correlates with redox status in Trypanosoma cruzi Nitric oxide and Brazilian propolis combined accelerates tissue repair by modulating cell migration, cytokine production and collagen deposition in experimental leishmaniasis.Advances in Chagas disease drug development: 2009-2010 In vitro effects of novel ruthenium complexes in Neospora caninum and Toxoplasma gondii tachyzoites.Therapeutical approaches under investigation for treatment of Chagas disease.Chagas disease drug discovery: toward a new era.Organometallic gold(iii) complexes with hybrid SNS-donating thiosemicarbazone ligands: cytotoxicity and anti-Trypanosoma cruzi activity.Thiol-Activated HNO Release from a Ruthenium Antiangiogenesis Complex and HIF-1α Inhibition for Cancer Therapy Antileishmanial Activity and Inducible Nitric Oxide Synthase Activation by RuNO Complex The latest advances in the discovery of nitric oxide hybrid drug compounds.Sodium nitroprusside has leishmanicidal activity independent of iNOS.Organometallic Derivatization of the Nematocidal Drug Monepantel Leads to Promising Antiparasitic Drug Candidates.Preconditioning with a novel metallopharmaceutical NO donor in anesthetized rats subjected to brain ischemia/reperfusion.Effects of Rut-bpy (Cis-[Ru(bpy)2(SO3)(NO)]PF 6), a novel nitric oxide donor, in L-NAME-induced hypertension in rats.

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P2860

Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity.

http://www.wikidata.org/entity/Q33870401

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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J.1476-5381.2009.00524.X

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British Journal of Pharmacology

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Aderson Zottis

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Adriano Defini Andricopulo

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Douglas Wagner Franco

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Francisco Ordelei Nascimento Silva

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Glaucius Oliva

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Jean Jerley Nogueira Silva

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João Santana Silva

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Luiz Gonzaga França Lopes

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Paulo Marcos Matta Guedes

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Tatiane Luciano Balliano

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P2860

Nitric oxide and peroxynitrite in health and disease

Oral drug therapy for multiple neglected tropical diseases: a systematic review

Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)

Protein S-nitrosylation: purview and parameters

Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi.

Glycolysis as a target for the design of new anti-trypanosome drugs.

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host.

The role of nitric oxide in the pathogenesis of Chagas disease.

Oxidative stress and antioxidant defenses: a target for the treatment of diseases caused by parasitic protozoa.

In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors

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