Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

Item
http://www.wikidata.org/entity/Q33874837
Neurotrophin and neurotrophin receptor proteins in medulloblastomas and other primitive neuroectodermal tumors of the pediatric central nervous system.Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma.The neurotrophin receptor, gp75, forms a complex with the receptor tyrosine kinase TrkACircular dichroism and crosslinking studies of the interaction between four neurotrophins and the extracellular domain of the low-affinity neurotrophin receptor.Identification of tyrosine kinase Trk as a nerve growth factor receptor.Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.Chimeric tumor necrosis factor-TrkA receptors reveal that ligand-dependent activation of the TrkA tyrosine kinase is sufficient for differentiation and survival of PC12 cellsExpression of trkA cDNA in neuroblastomas mediates differentiation in vitro and in vivo.The low-affinity p75 nerve growth factor (NGF) receptor mediates NGF-induced tyrosine phosphorylation.A novel apoptotic pathway induced by nerve growth factor-mediated TrkA activation in medulloblastoma.Primitive neuroectodermal tumors of the central nervous system.Spectroscopic and chemical studies of the interaction between nerve growth factor (NGF) and the extracellular domain of the low affinity NGF receptor.The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.Nerve growth factor receptor expression in peripheral and central neuroectodermal tumors, other pediatric brain tumors, and during development of the adrenal gland.Concentration-dependent regulation of neuronal gene expression by nerve growth factor.Monoclonal antibodies to a rat nestin fusion protein recognize a 220-kDa polypeptide in subsets of fetal and adult human central nervous system neurons and in primitive neuroectodermal tumor cells.Ectopic trkA expression mediates a NGF survival response in NGF-independent sensory neurons but not in parasympathetic neurons.
P2860

Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

Item
http://www.wikidata.org/entity/Q33874837
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Introduction of nerve growth f ...... NGF-mediated differentiation.
@ast
Introduction of nerve growth f ...... NGF-mediated differentiation.
@en
type
label
Introduction of nerve growth f ...... NGF-mediated differentiation.
@ast
Introduction of nerve growth f ...... NGF-mediated differentiation.
@en
prefLabel
Introduction of nerve growth f ...... NGF-mediated differentiation.
@ast
Introduction of nerve growth f ...... NGF-mediated differentiation.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Introduction of nerve growth f ...... NGF-mediated differentiation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932