The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.
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Long-Term Potentiation and MemoryNeurotrophin 3 is a mitogen for cultured neural crest cellstrkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificitiesTargeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neuronsRON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSPSequence-specific targeting of nuclear signal transduction pathways by homeodomain proteinsEffect of Estradiol on Neurotrophin Receptors in Basal Forebrain Cholinergic Neurons: Relevance for Alzheimer's DiseaseHigh resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptorsAssociation of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disordersBinding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkCMolecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptorsMuscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain.Cell-cycle arrest in TrkA-expressing NIH3T3 cells involves nitric oxide synthase.Neurotrophin 3 rescues neuronal precursors from apoptosis and promotes neuronal differentiation in the embryonic metanephric kidney.Mechanisms of activation of receptor tyrosine kinases: monomers or dimers.A function-structure model for NGF-activated TRKDtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.Is bone a target-tissue for the nervous system? New advances on the understanding of their interactionsAn extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.The trk family of receptors mediates nerve growth factor and neurotrophin-3 effects in melanocytes.Induction of serpinb1a by PACAP or NGF is required for PC12 cells survival after serum withdrawalGanglioside GM1 binds to the Trk protein and regulates receptor function.TrkA cross-linking mimics neuronal responses to nerve growth factorThe p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron deathThe trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3Expression of TrkA confers neuron-like responsiveness to nerve growth factor on an immortalized hypothalamic cell linep75(NTR) mediates neurotrophin-induced apoptosis of vascular smooth muscle cells.Cellular localization of the Trk neurotrophin receptor family in human non-neuronal tissues.Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injuryAssociation of neurotrophin receptor expression and differentiation in human neuroblastoma.An alternatively spliced form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin 3.Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth.Regulation of nerve growth factor receptor gene expression in sympathetic neurons during developmentExpression of functional trk protooncogene in human monocytesNeuronal colocalization of mRNAs for neurotrophins and their receptors in the developing central nervous system suggests a potential for autocrine interactions.Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases.Role of neurotrophic factors in early ovarian developmentDifferential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.Chimeric tumor necrosis factor-TrkA receptors reveal that ligand-dependent activation of the TrkA tyrosine kinase is sufficient for differentiation and survival of PC12 cellsSNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.
P2860
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P2860
The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The trk tyrosine protein kinas ...... wth factor and neurotrophin-3.
@en
type
label
The trk tyrosine protein kinas ...... wth factor and neurotrophin-3.
@en
prefLabel
The trk tyrosine protein kinas ...... wth factor and neurotrophin-3.
@en
P2093
P2860
P1433
P1476
The trk tyrosine protein kinas ...... wth factor and neurotrophin-3.
@en
P2093
C Cordon-Cardo
E O'Rourke
F Lamballe
L F Reichardt
P2860
P304
P356
10.1016/0092-8674(91)90149-S
P407
P577
1991-07-01T00:00:00Z