Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase.
about
Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolasesDirected Evolution and Structural Characterization of a Simvastatin SynthaseMechanistic approaches to the study of evolution: the functional synthesisDirected evolution: an approach to engineer enzymes.In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD).Design and directed evolution of a dideoxy purine nucleoside phosphorylase.Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates.Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251.Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis.Directed evolution of aldolases for exploitation in synthetic organic chemistryPrediction of distal residue participation in enzyme catalysis.Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates.Molecular characterization of a novel N-acetylneuraminate lyase from Lactobacillus plantarum WCFS1.Synthesis of a 3-deoxy-D-manno-octulosonic acid (KDO) building block from D-glucose via fermentation.Enzymatic synthesis of 3-deoxy-d-manno-octulosonic acid (KDO) and its application for LPS assembly.Role of conformational dynamics in the evolution of novel enzyme function.
P2860
Q27640837-59943CFC-F36C-485B-9A0F-5857C637EBE8Q27658016-057A3B91-AB67-416B-8FB5-277790602E2FQ28757580-F606EFEA-D377-4747-88D3-87384A9C1409Q33254710-C2101516-8FEF-4DB1-900F-5EFF201ED674Q33287890-EFF84E47-1047-4291-B121-EC98D22D4A19Q33967613-8AE5724A-33D0-4069-AE10-851FC244743FQ34153625-964742C9-BBC3-4CEF-BB73-E57091F085B4Q34800041-22B9BA90-FB72-4ED3-B6C9-FF9190E91779Q35161643-BC9A3362-0BB0-46BF-9CE7-4B25B2D4B240Q37071273-91D4E0CF-495B-4DB9-B193-772110D8A1AEQ40296149-AE726B07-6B3A-4018-A2DD-936D8C59DA41Q42099105-AF0342F3-38B7-4D5B-A82A-976FFAC8E992Q42120492-5BA663FE-1417-479D-B49B-B263A5E515D8Q54338545-D09B257B-2C5B-4AEF-87C3-951D1E2EAE80Q55265311-5814D39B-704D-4FF5-8C89-E91B43E0452BQ55689469-528F06EA-5014-4982-90A7-E84591E18643
P2860
Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@ast
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@en
type
label
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@ast
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@en
prefLabel
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@ast
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@en
P2093
P2860
P356
P1476
Directed evolution of D-sialic ...... losonic acid (L-KDO) aldolase.
@en
P2093
Che-Chang Hsu
Chi-Huey Wong
Dirk Franke
Masaru Wada
Zhangyong Hong
P2860
P304
P356
10.1073/PNAS.0504033102
P407
P577
2005-06-20T00:00:00Z