Alternative splicing and alternative initiation of translation explain the four forms of the Ia antigen-associated invariant chain.
about
Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodesSequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733Friends and relations of the cystatin superfamily--new members and their evolutionMajor histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin LInvariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigensMapping functional regions in the lumenal domain of the class II-associated invariant chainCrystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.The p41 isoform of invariant chain is a chaperone for cathepsin LStructural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide bindingMacrophage migration inhibitory factor down-regulates the RANKL-RANK signaling pathway by activating Lyn tyrosine kinase in mouse modelsIdentification of the glycosaminoglycan-attachment site of mouse invariant-chain proteoglycan core protein by site-directed mutagenesisTargeting a polyepitope protein incorporating multiple class II-restricted viral epitopes to the secretory/endocytic pathway facilitates immune recognition by CD4+ cytotoxic T lymphocytes: a novel approach to vaccine design.The invariant chain forms complexes with class II major histocompatibility complex molecules and antigenic peptides "in vivo".Interaction of human immunodeficiency virus type 2 Vpx and invariant chain.A retroviral mutagenesis screen identifies Cd74 as a common insertion site in murine B-lymphomas and reveals the existence of a novel IFNgamma-inducible Cd74 isoformPrimary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulinStable surface expression of invariant chain prevents peptide presentation by HLA-DR.Boosting immune response with the invariant chain segments via association with non-peptide binding region of major histocompatibility complex class II molecules.Coreceptor restriction within the HLA-DQ locus for Epstein-Barr virus infectionExit of major histocompatibility complex class II-invariant chain p35 complexes from the endoplasmic reticulum is modulated by phosphorylation.Exogenous Thyropin from p41 Invariant Chain Diminishes Cysteine Protease Activity and Affects IL-12 Secretion during Maturation of Human Dendritic CellsRelationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.Invariant chain controls the activity of extracellular cathepsin L.Contributions of MYOC and CYP1B1 mutations to JOAGRelationship between elevated soluble CD74 and severity of experimental and clinical ALI/ARDSExposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome.MHC class II antigen presentation by dendritic cells regulated through endosomal sorting.Invariant Chain Complexes and Clusters as Platforms for MIF Signaling.Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules.In vitro generation of a circular exon from a linear pre-mRNA transcript.Sequence of a rat MHC class II-associated invariant chain cDNA clone containing a 64 amino acid thyroglobulin-like domain.Shark class II invariant chain reveals ancient conserved relationships with cathepsins and MHC class II.Complete sequence of the murine invariant chain (Ii) geneAssembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II moleculesIntracellular transport and localization of major histocompatibility complex class II molecules and associated invariant chain.
P2860
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P2860
Alternative splicing and alternative initiation of translation explain the four forms of the Ia antigen-associated invariant chain.
description
1986 nî lūn-bûn
@nan
1986 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Alternative splicing and alter ...... en-associated invariant chain.
@ast
Alternative splicing and alter ...... en-associated invariant chain.
@en
type
label
Alternative splicing and alter ...... en-associated invariant chain.
@ast
Alternative splicing and alter ...... en-associated invariant chain.
@en
prefLabel
Alternative splicing and alter ...... en-associated invariant chain.
@ast
Alternative splicing and alter ...... en-associated invariant chain.
@en
P2093
P2860
P1433
P1476
Alternative splicing and alter ...... en-associated invariant chain.
@en
P2093
P2860
P304
P407
P577
1986-12-01T00:00:00Z