Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2.
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Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundleThe TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activationChemokine blockade: a new era in the treatment of rheumatoid arthritis?Solution structure and dynamics of myeloid progenitor inhibitory factor-1 (MPIF-1), a novel monomeric CC chemokineHuman Macrophage Inflammatory Protein 3 : Protein and Peptide Nuclear Magnetic Resonance Solution Structures, Dimerization, Dynamics, and Anti-Infective PropertiesSolution Structure of CCL21 and Identification of a Putative CCR7 Binding SiteMultimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxisDominant-negative mutation of monocyte chemoattractant protein-1 prevents vulnerable plaques from rupture in rabbits independent of serum lipid levelsEmerging concepts and approaches for chemokine-receptor drug discovery.Chemokine receptor oligomerization and allostery.Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitorSmall molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptorsDynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation.Identification of CCR2-binding features in Cytl1 by a CCL2-like chemokine model.A competitive binding study of chemokine, sulfated receptor, and glycosaminoglycan interactions by nano-electrospray ionization mass spectrometry.Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors.Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 functionCrystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.Design and receptor interactions of obligate dimeric mutant of chemokine monocyte chemoattractant protein-1 (MCP-1).Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptorsTyrosine sulfation of chemokine receptor CCR2 enhances interactions with both monomeric and dimeric forms of the chemokine monocyte chemoattractant protein-1 (MCP-1)Chemokine oligomerization in cell signaling and migration.CCL2 nitration is a negative regulator of chemokine-mediated inflammation.Chemokine oligomerization and interactions with receptors and glycosaminoglycans: the role of structural dynamics in functionUnique role of the chemokine domain of fractalkine in cell capture. Kinetics of receptor dissociation correlate with cell adhesion.Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach.Chemokines and their receptors: insights from molecular modeling and crystallography.Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16.Rationally evolving MCP-1/CCL2 into a decoy protein with potent anti-inflammatory activity in vivo.Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin.The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.CXCR3 and heparin binding sites of the chemokine IP-10 (CXCL10).Biotinylated synthetic chemokines: their use for the development of nonradioactive whole-cell binding assays.Specificity determinants for chemokine recognition identified using eotaxin-MCP-1 chimeras.
P2860
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P2860
Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification of surface resi ...... ing through the receptor CCR2.
@ast
Identification of surface resi ...... ing through the receptor CCR2.
@en
type
label
Identification of surface resi ...... ing through the receptor CCR2.
@ast
Identification of surface resi ...... ing through the receptor CCR2.
@en
prefLabel
Identification of surface resi ...... ing through the receptor CCR2.
@ast
Identification of surface resi ...... ing through the receptor CCR2.
@en
P2093
P356
P1433
P1476
Identification of surface resi ...... ing through the receptor CCR2.
@en
P2093
Freedman R
Grunberger D
Hemmerich S
Jarnagin K
McCarley D
P304
16167-16177
P356
10.1021/BI9912239
P407
P577
1999-12-01T00:00:00Z