Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. - Wikidata - awgldk - TriplyDB

Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance.

Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance.

http://www.wikidata.org/entity/Q33882773

about

Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights Adipose extracellular matrix remodelling in obesity and insulin resistance Omentum and bone marrow: how adipocyte-rich organs create tumour microenvironments conducive for metastatic progression Thrombospondin-1 mediates multi-walled carbon nanotube induced impairment of arteriolar dilation Presence of anti-ADAMTS13 antibodies in obesity.Defective ADAMTS13 synthesis as a possible consequence of NASH in an obese patient with recurrent thrombotic thrombocytopenic purpura.Adipose tissue lipolysis and remodeling during the transition period of dairy cows Thrombospondin-1 is an inhibitor of pharmacological activation of soluble guanylate cyclase.Glucose downregulation of PKG-I protein mediates increased thrombospondin1-dependent TGF-{beta} activity in vascular smooth muscle cells Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model.Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation.Chronic delivery of a thrombospondin-1 mimetic decreases skeletal muscle capillarity in mice Global gene expression profiles of subcutaneous adipose and muscle from glucose-tolerant, insulin-sensitive, and insulin-resistant individuals matched for BMI.Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone.Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity Thrombospondin-1: multiple paths to inflammation.Vascular biology of metabolic syndrome CD47 deficiency protects mice from diet-induced obesity and improves whole body glucose tolerance and insulin sensitivity.Maternal plasma protein profiles in response to oral 50-gram glucose load in mid-pregnancy: a pilot study Thrombospondin1 deficiency attenuates obesity-associated microvascular complications in ApoE-/- mice Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation.Hematological and acute-phase responses to diet-induced obesity in IL-6 KO mice.Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells.Interaction of thrombospondin1 and CD36 contributes to obesity-associated podocytopathy.Inflammatory pathway genes belong to major targets of persistent organic pollutants in adipose cells.Effects of High Fat Feeding on Adipose Tissue Gene Expression in Diabetic Goto-Kakizaki Rats Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities.PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis.Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus.Omega-3 fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance.In Vivo Functional Evaluation of Tissue-Engineered Vascular Grafts Fabricated Using Human Adipose-Derived Stem Cells from High Cardiovascular Risk Populations Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects Oxidative stress regulates adipocyte apolipoprotein e and suppresses its expression in obesity.

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P2860

Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance.

http://www.wikidata.org/entity/Q33882773

description

2007 nî lūn-bûn

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2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Thrombospondin-1 is an adipoki ...... ation, and insulin resistance.

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Thrombospondin-1 is an adipoki ...... ation, and insulin resistance.

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Thrombospondin-1 is an adipoki ...... ation, and insulin resistance.

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Thrombospondin-1 is an adipoki ...... ation, and insulin resistance.

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Thrombospondin-1 is an adipoki ...... ation, and insulin resistance.

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Thrombospondin-1 is an adipoki ...... ation, and insulin resistance.

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Aiwei Yao-Borengasser

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Angela M Bodles

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Bounleut Phanavanh

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Charlotte A Peterson

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Emily M Kern

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Greg T Nolen

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Horace J Spencer

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Philip A Kern

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Radhakrishnan Nagarajan

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Robert E McGehee

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P2860

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Nuclear receptor corepressors and PPARgamma

Obesity is associated with macrophage accumulation in adipose tissue

Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology

Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

Thrombospondins as matricellular modulators of cell function.

Gene expression in visceral and subcutaneous adipose tissues.

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction.

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