GAB2 amplifications refine molecular classification of melanoma. - Wikidata - awgldk - TriplyDB

GAB2 amplifications refine molecular classification of melanoma.

GAB2 amplifications refine molecular classification of melanoma.

http://www.wikidata.org/entity/Q33883923

about

Function, regulation and pathological roles of the Gab/DOS docking proteins Grb2-associated binding (Gab) proteins in hematopoietic and immune cell biology Structure and function of Gab2 and its role in cancer (Review)Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation Superficial spreading and nodular melanoma are distinct biological entities: a challenge to the linear progression model.Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.Gab2 is a novel prognostic factor for colorectal cancer patients The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence Genetic alterations in RAS-regulated pathway in acral lentiginous melanoma Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumour DNA with SERS Nanotags.GAB2 induces tumor angiogenesis in NRAS-driven melanoma.Docking proteins.The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways.Clinical significance of GAB2, a scaffolding/docking protein acting downstream of EGFR in human colorectal cancer.Functional characterization of cancer-associated Gab1 mutations.Genomic characterisation of acral melanoma cell lines.Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene.Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma.GAB2 Amplification in Squamous Cell Lung Cancer of Non-Smokers.Combined detection of Gab1 and Gab2 expression predicts clinical outcome of patients with glioma.The clinical significance of c-Kit mutations in metastatic oral mucosal melanoma in China.BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.

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P2860

GAB2 amplifications refine molecular classification of melanoma.

http://www.wikidata.org/entity/Q33883923

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

GAB2 amplifications refine molecular classification of melanoma.

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GAB2 amplifications refine molecular classification of melanoma.

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type

label

GAB2 amplifications refine molecular classification of melanoma.

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GAB2 amplifications refine molecular classification of melanoma.

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prefLabel

GAB2 amplifications refine molecular classification of melanoma.

@ast

GAB2 amplifications refine molecular classification of melanoma.

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Clinical Cancer Research

P1476

GAB2 amplifications refine molecular classification of melanoma.

@en

P2093

Basil Horst

http://www.w3.org/2001/XMLSchema#string

David N Silvers

http://www.w3.org/2001/XMLSchema#string

Georg Brunner

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Jason A Cohen

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Julide Tok Celebi

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Karen A Chernoff

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Katherine Simon

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Keagan Lee

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Lindsey Bordone

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Shuang Wang

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P2860

A bacterial artificial chromosome library for sequencing the complete human genome

Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha

Mutations of the BRAF gene in human cancer

Determinants of BRAF mutations in primary melanomas

Distinct sets of genetic alterations in melanoma

Challenges in array comparative genomic hybridization for the analysis of cancer samples.

Somatic activation of KIT in distinct subtypes of melanoma.

The "Gab" in signal transduction.

Toward a molecular classification of melanoma.

Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.

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4288-4291

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10.1158/1078-0432.CCR-09-0280

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