Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.
about
Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cordAttenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cordRab23 negatively regulates Gli1 transcriptional factor in a Su(Fu)-dependent mannerGenome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitorsTemporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over timeFoxa1 and Foxa2 are required for formation of the intervertebral discsFoxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signallingIntegration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversityAntagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling.Coordination of progenitor specification and growth in mouse and chick spinal cordSonic hedgehog elevates N-myc gene expression in neural stem cells.Glycoconjugates distribution during developing mouse spinal cord motor organizers.Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei.Dorsoventral patterning of the Xenopus eye involves differential temporal changes in the response of optic stalk and retinal progenitors to Hh signalling.Reconstruction of the gene regulatory network involved in the sonic hedgehog pathway with a potential role in early development of the mouse brainPtch1 and Gli regulate Shh signalling dynamics via multiple mechanisms.Cell lineage branching as a strategy for proliferative control.A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog ResponseA conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.Dynamics of BMP and Hes1/Hairy1 signaling in the dorsal neural tube underlies the transition from neural crest to definitive roof plate.Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage.Duration of Shh signaling contributes to mDA neuron diversityInductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.Temporal control of BMP signalling determines neuronal subtype identity in the dorsal neural tube.The transition from differentiation to growth during dermomyotome-derived myogenesis depends on temporally restricted hedgehog signaling.Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional ProgramsRetinoid acid specifies neuronal identity through graded expression of Ascl1.Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus.Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.Mechanisms of Hedgehog signalling in cancer.Spatiotemporal mechanisms of morphogen gradient interpretationThe notochord: structure and functions.The effects of the toxic cyanobacterium Limnothrix (strain AC0243) on Bufo marinus larvae.Establishing diversity in the dopaminergic system.Directed Differentiation of V3 Interneurons from Mouse Embryonic Stem Cells.John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work?Essential roles of fibronectin in the development of the left-right embryonic body plan.
P2860
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P2860
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@ast
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@en
type
label
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@ast
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@en
prefLabel
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@ast
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@en
P2093
P2860
P50
P356
P1433
P1476
Distinct Sonic Hedgehog signal ...... in the vertebrate neural tube.
@en
P2093
Ben Novitch
Elisa Marti
Lin Lin Yang
Nikolaos Balaskas
Samuel Tozer
P2860
P304
P356
10.1101/GAD.559910
P577
2010-06-01T00:00:00Z