S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes.
about
Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transductionABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stabilityThe influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activationNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activityA novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane eventsSpatial and temporal regulation of protein kinase D (PKD)Caveolae/lipid rafts in fibroblast-like synoviocytes: ectopeptidase-rich membrane microdomainsClustering induces redistribution of syndecan-4 core protein into raft membrane domainsTranslocation of CD28 to lipid rafts and costimulation of IL-2CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signalingCharacterization of the in vivo sites of serine phosphorylation on Lck identifying serine 59 as a site of mitotic phosphorylation.The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling.Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells.T-cell receptor microclusters critical for T-cell activation are formed independently of lipid raft clusteringCD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.The PTI1-like kinase ZmPti1a from maize (Zea mays L.) co-localizes with callose at the plasma membrane of pollen and facilitates a competitive advantage to the male gametophyteDirect observation and quantitative analysis of Lck exchange between plasma membrane and cytosol in living T cells.IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinasesDynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.Signal transduction via CD44: role of plasma membrane microdomains.rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases.Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains.Tandem fluorescence imaging of dynamic S-acylation and protein turnover.Endocytosis of nanomedicines.Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes.TCR signal initiation machinery is pre-assembled and activated in a subset of membrane raftsA role for lipid rafts in immune cell signaling.IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.The transmembrane adapter LAT plays a central role in immune receptor signalling.CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts.Glycosylphosphatidylinositol-anchored proteins: structure, function, and cleavage by phosphatidylinositol-specific phospholipase C.CTLA-4 negative signaling via lipid rafts: A new perspective.Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage.The roles of membrane microdomains (rafts) in T cell activation.Use of analogs and inhibitors to study the functional significance of protein palmitoylation.Rosmarinic acid as a downstream inhibitor of IKK-beta in TNF-alpha-induced upregulation of CCL11 and CCR3.Use of detergents to study membrane rafts: the good, the bad, and the ugly.Plasma membrane microdomains: organization, function and trafficking.Control of immune responses by trafficking cell surface proteins, vesicles and lipid rafts to and from the immunological synapse.
P2860
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P2860
S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes.
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@ast
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@en
type
label
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@ast
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@en
prefLabel
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@ast
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@en
P2093
P2860
P356
P1433
P1476
S-acylation of LCK protein tyr ...... ing function in T lymphocytes.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/16.16.4983
P407
P577
1997-08-01T00:00:00Z