Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice. - Wikidata - awgldk - TriplyDB

Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.

Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.

http://www.wikidata.org/entity/Q33888375

about

Janus kinases in immune cell signaling Inflammatory pathways of importance for management of inflammatory bowel disease Genetic deletion of Mst1 alters T cell function and protects against autoimmunity Time-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T Lymphocytes NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3 Interleukin-7 mediates glucose utilization in lymphocytes through transcriptional regulation of the hexokinase II gene Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited.JAK inhibition for the treatment of rheumatoid arthritis: a new era in oral DMARD therapy.Tofacitinab in renal transplantation.Cytokines and immunodeficiency diseases.Janus kinase-3 dependent inflammatory responses in allergic asthma Death and Baxes: mechanisms of lymphotrophic cytokines.Janus kinase 3: the controller and the controlled Janus kinase-3 (JAK3) inhibition: a novel immunosuppressive option for allogeneic transplantation.Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis?Lymphocyte development: integration of DNA damage response signaling.Interlinking interleukin-7.Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models.Kinase inhibitors for the treatment of inflammatory and autoimmune disorders.Differential requirement of the cytoplasmic subregions of gamma c chain in T cell development and function.IL-2 pathway blocking in combination with anti-CD154 synergistically establishes mixed macrochimerism with limited dose of bone marrow cells and prolongs skin graft survival in mice STAT3 targets suggest mechanisms of aggressive tumorigenesis in diffuse large B-cell lymphoma.The function of cancer-shed gangliosides in macrophage phenotype: involvement with angiogenesis.IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis Selective JAK1 inhibitor and selective Tyk2 inhibitor patents.Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.The common γ-chain cytokine receptor: tricks-and-treats for T cells.Synergistic effects of interleukin-7 and pre-T cell receptor signaling in human T cell development.Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit.Selective Inhibition of Janus Kinase 3 Has No Impact on Infarct Size or Neurobehavioral Outcomes in Permanent Ischemic Stroke in Mice Direct interaction between Kit and the interleukin-7 receptor.Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients.Comparative study of human hematopoietic cell engraftment into BALB/c and C57BL/6 strain of rag-2/jak3 double-deficient mice.Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals.The novel JAK-3 inhibitor CP-690550 is a potent immunosuppressive agent in various murine models.Janus kinase 3: a novel target for selective transplant immunosupression.IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.Janus kinase 3-deficient T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs.The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.Cytokine Receptors

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Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.

http://www.wikidata.org/entity/Q33888375

description

2000 nî lūn-bûn

@nan

2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի փետրվարին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

@wuu

name

Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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type

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Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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International Immunology

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Janus kinase 3 (Jak3) is essen ...... nd Jak3 double-deficient mice.

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P2093

Iwamoto I

http://www.w3.org/2001/XMLSchema#string

Leonard WJ

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Nakajima H

http://www.w3.org/2001/XMLSchema#string

Saito T

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Saito Y

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Suzuki K

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P2860

Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM

STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression

Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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123-132

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scholarly article

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10.1093/INTIMM/12.2.123

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2

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12

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12660644

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10653847

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